Tivortin Aspartate: a New Safe and Effective Non-Prohibited Medical Drug for Stimulation the Performance of Athletes
Journal Title: Український журнал медицини, біології та спорту - Year 2017, Vol 5, Issue 3
Abstract
The need to increase sport achievements in the setting of ever-increasing competition and approximation of the functional capabilities of the human body to the border of reserve mechanisms make us seek new ways to stimulate physical performance and psycho-emotional stability of athletes. One of the most promising areas for improving the results of training and competitive activities of athletes is the use of pharmacological agents which are not prohibited by WADA. At the present time the substances that are on L-arginine based, in the form of food supplements firmly took their place in the pharmacological support of children’s and youth sport and high performance sport. Materials and Methods. Studies of the safety and efficacy of Tivortin aspartate (L-arginine aspartate) were conducted in skilled male athletes aged 18 to 26, represented the different groups of sports – cyclic (track and field athletics, middle distance running) and endurance (weightlifting) ones. The study involved 69 healthy skilled (first-rate and sub-master sportsmen) athletes who were on a special preparatory stage of the preparatory period of the annual macrocycle in the standard training mode. All study participants had no manifestations of any acute respiratory viral infections and the history of diseases of cardio-respiratory, endocrine, digestive, excretory systems with clinical manifestations. The athletes signed Informed Consent, in which they confirmed their voluntary consent to participate in the study after acquaintance with all its features that could affect their free decision. The study was randomized, blind and placebo-controlled. Randomization of the athletes within both groups(Group 1 – 36 track and field athletes, Group 2 – 33 weightlifters) was conducted before the signing the Informed Consent. By simple randomization within the groups, 4 subgroups of athletes (2 main and 2 control) were formed; they did not have statistically significant differences in the initial clinic and anamnestic, anthropologic and demographic, pedagogical, qualification and gender characteristics. Treatment groups included 46 athletes, of them 24 middle distance runners and 22 weightlifters, and 23 athletes as controls (12 runners and 11 weightlifters). Tivortin aspartate as a 20 % oral solution at a daily dose of 40 ml, divided into two 20 ml
Authors and Affiliations
L. Gunina, Yu. Vinnichuk, A. Dmitriev, N. Vysochina, V. Bezuglaya, E. Nosach
Keywords
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