To Assess the Diagnostic Accuracy of MRI in Intracranial Space Occupying Lesions
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Background: Intracranial space occupying lesions are a major cause of morbidity and mortality in the productive age-group of human beings. Non-specific and late-onset symptoms are often responsible for delay in diagnosis in majority of the cases. Imaging plays a pivotal role not only in the detection but also in accurate diagnosis of these lesions affecting management and further progress of the disease. Advent of newer techniques in MRI like diffusion weighted imaging (DWI) and magnetic resonance spectroscopy (MRS) have prompted us to conduct this study comparing the role of imaging in reaching the final diagnosis in the present scenario. Materials & Methods: Thirty patients of variable age and sex showing intracranial space occupying lesion on imaging were included in our study. Final MRI diagnosis was made using conventional & newer MRI techniques and the results were compared with the final histopathology / clinical diagnosis with follow-up. Additionally, the impact of newer MRI techniques on final diagnosis was also studied. Results & Conclusion: Out of a total of thirty patients, histopathology could be achieved in 29 patients and the remaining one patient of tuberculoma was treated medically & followed up till near-complete resolution of the lesion. Peripheral ADC values on DWI and higher Cho:NAA & Cho:Cr ratios on MRS were found to be specific markers of malignancy and high-grade tumors. Though our study has a small sample size yet when conventional MRI technique was coupled with DWI & MRS, more than 90% sensitivity & specificity could be achieved.
Authors and Affiliations
Pankaj Kumar Das, Rajul Rastogi, Abhishek Aggarwal, Vijai Pratap, Arvind Shukla, Narendra Kumar, Shyamoli Dutta
Keywords
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- EP ID EP531087
- DOI 10.21276/ijmrp.2018.4.1.111
- Views 81
- Downloads 0
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