To clip or not to clip the breast tumor bed? A retrospective look at the geographic miss index and normal tissue index of 110 patients with breast cancer
Journal Title: UNKNOWN - Year 2017, Vol 18, Issue 2
Abstract
Objective: Planning of breast radiation for patients with breast conserving surgery often relies on clinical markers such as scars. Lately, surgical clips have been used to identify the tumor location. The purpose of this study was to evaluate the geographic miss index (GMI) and the normal tissue index (NTI) for the electron boost in breast cancer treatment plans with and without surgical clips. Material and Methods: A retrospective descriptive study of 110 consecutive post-surgical patients who underwent breast-conserving treatment in early breast cancer, in which the clinical treatment field with the radiologic (clipped) field were compared and GMI/NTI for the electron boost were calculated respectively. Results: The average clinical field was 100 mm (range, 100-120 mm) and the clipped field was 90 mm (range, 80-100 mm). The average GMI was 11.3% (range, 0-44%), and the average NTI was 27.5% (range, 0-54%). The GMI and NTI were reduced through the use of intra-surgically placed clips. Conclusion: The impact of local tumor control on the survival of patients with breast cancer is also influenced by the precision of radiotherapy. Additionally, patients demand an appealing cosmetic result. This makes “clinical” markers such as scars unreliable for radiotherapy planning. A simple way of identifying the tissue at risk is by intra-surgical clipping of the tumor bed. Our results show that the use of surgical clips can reduce the diameter of the radiotherapy field and increase the accuracy of radiotherapy planning. With the placement of surgical clips, more tissue at risk is included in the radiotherapy field. Less normal tissue receives radiotherapy with the use of surgical clips.
Authors and Affiliations
Florian Ebner, Nikolaus de Gregorio, Andreas Rempen, Peter Mohr, Amelie de Gregorio, Achim Wöckel, Wolfgang Janni, Gerlo Witucki
Keywords
Related Articles
- EP ID EP379943
- DOI 10.4274/jtgga.2016.0222
- Views 50
- Downloads 0
The impact of different 75 g oral glucose tolerance test target ranges within normal limits on neonatal outcomes: A validation study
Objective: To investigate the impact of different 75 g glucose tolerance test (OGTT) target ranges within normal limits on neonatal outcomes, thus to investigate the validity of 75 g OGTT thresholds. Materials and Metho...
Communication, orientation, coordination: A model for a laparoscopy team
.
Dual trigger with gonadotropin-releasing hormone and human chorionic gonadotropin for poor responders
Objective: To compare metaphase II (MII) rate, fertilization rate, and embryo quality with dual trigger gonadotropin-releasing hormone agonist (GnRH) and normal dose human chorionic gonadotropin (hCG) versus a normal dos...
The assessment of thyroid autoantibody levels in euthyroid patients with polycystic ovary syndrome
Objective: Thyroid hormone abnormalities are commonly seen in polycystic ovary syndrome (PCOS) and have considerable effects on comorbidities. The association with PCOS and thyroid autoimmunity which lead to thyroid path...
The level of using family planning methods and factors that influence the preference of methods in the Konya-Meram area
Objective: To determine the level of contraceptive method use and factors that influence the preference of method among women of reproductive age that live in Meram, the central district of Konya. Material and Methods:...