To compare empirical treatment of uncomplicated UTI in pregnancy
Journal Title: Indian Journal of Obstetrics and Gynecology Research - Year 2018, Vol 5, Issue 3
Abstract
Objectives To compare empirical treatment with fosfomycin and nitrofurantoin in uncomplicated lower urinary tract infection during pregnancyMaterials and Methods Patients were recruited from OPD of obstetrics and gynecology presenting with symptoms of lower UTIs urinary tract infection Patients were divided randomly alternately in two groups Fosfomycin therapy was given in group 1 n60 and seven days nitrofurantoin therapy was given in group 2n60 Patients were evaluated for symptoms improvement compliance side effects and cost of treatmentResults Efficacy of fosfomycin on day 7 post treatment is 98 compare to nitrofrantoin I s833 Side effect is 15 in fosfomycin group as compare to 283 in nitrofurantoin group Compliance is 100 in fosfomycin group as compare to 966 in nitrofrantoin group Cost of therapy in fosfomycin group is 300 Rs average while 170 Rs in nitrofurantoin groupConclusion Fosfomycin is first line empirical treatment of uncomplicated UTIs during pregnancy because it is safe effective less resistance higher patients compliance with fewer side effect and equal cost of therapyKeywords Pregnancy Cystitis Nitrofurantoin Fosfomycin UTIs
Authors and Affiliations
Vipul S. Patel
Keywords
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- EP ID EP475138
- DOI 10.18231/2394-2754.2018.0083
- Views 63
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