TO COMPARE IONIC VERSUS NONIONIC CONTRAST MEDIA IN RENAL ANGIOGRAPHY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 39
Abstract
BACKGROUND The adverse effects of ionic and nonionic contrast media, were compared in a group of 44 healthy renal donors undergoing renal angiography as a screening procedure, for adverse reactions and change in renal function. MATERIALS AND METHODS 44 healthy renal donors, with normal renal function and no associated co-morbid conditions, who underwent renal angiography under DSA as a screening procedure for renal assessment were selected. Of them, 22 donors were randomly chosen to be given ionic contrast medium (Diatrizoate Sodium, Diatrizoate Meglumine) and 22 nonionic contrast medium (Iohexol and Iopamidol), in the dosage of 1 ml/kg body weight. They were assessed pre and 48 hours post procedure for vitals and laboratory assessment of blood (blood urea, serum creatinine), Urine (specific gravity, proteins, RBC etc.) and GFR by DTPA scan. RESULTS Only mild type of adverse reactions like injection site pain, feeling of warmth and nausea were noted in both the groups. No adverse reactions of moderate or severe type were noted in either group. No significant change in the renal function was noted in both the groups as assessed by blood analysis (blood urea & Serum creatinine), urine analysis and GFR by DTPA scan 48 hours post contrast administration. CONCLUSION These results suggest that in dosage of 1ml/kg body weight, which is adequate for good opacification and necessary clinical information, ionic contrast media are as safe as more expensive nonionic media in healthy patients with no co-morbid conditions.
Authors and Affiliations
Sonica Sharma
Keywords
Related Articles
- EP ID EP572349
- DOI 10.18410/jebmh/2018/569
- Views 80
- Downloads 0
PRIMARY PAPILLARY ADENOCARCINOMA OF VAGINA: A RARE CASE REPORT
Primary vaginal adenocarcinoma is a rare malignant gynaecologic disease. A 56 year-old woman with post hysterectomy status presented with vaginal bleeding. She had a proliferative growth in the posterior vaginal wall ext...
CONJUNCTIVAL AUTOGRAFTING WITH AND WITHOUT SUTURES IN PTERYGIUM- A COMPARATIVE STUDY
BACKGROUND A prospective, randomised case-control study conducted at a tertiary level eye care center to compare the outcomes of Conjunctival Autograft (CAG) with sutures and CAG with patients’ own blood acting as a bioa...
INDUSTRIAL OCULAR TRAUMA- A CLINICAL AND EPIDEMIOLOGICAL PROFILE
BACKGROUND Incidence of ocular injuries is on the rise and is the commonest cause of unilateral blindness. Some individuals are at increased risk of eye injury as a result of their occupation. MATERIALS AND METHODS Data...
ACUTE LEUKAEMIA IMMUNOPHENOTYPING BY IMMUNOHISTOCHEMISTRY IN BONE MARROW TREPHINE BIOPSY SECTIONS
BACKGROUND Classification of acute leukaemia is gaining importance as the treatment continues to evolve for specific genetic and pathogenetic subgroups. AIMS: A well organised panel of antibodies can be used for immunoph...
DIFFERENTIATING PERIMORTEM AND POSTMORTEM BURNING
One of the most challenging cases in forensic medicine is ascertaining the cause of death of burnt bodies under suspicious circumstances. The key questions that arise at the time of investigation include:1 Was the pers...