TO COMPARE THE EFFECT OF CHITOSAN, LIFESTYLE MODIFICATION, AND COMBINATION OF CHITOSAN AND LIFESTYLE MODIFICATION ON BODY MASS INDEX IN OBESE PATIENTS
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2019, Vol 12, Issue 7
Abstract
Objective: The objective of this study was to compare the effect of chitosan, lifestyle modification, and combination of chitosan and lifestyle modification on body mass index (BMI) in obese patients. Methods: A prospective, randomized, open-label comparative study conducted for the period of 24 weeks. The study population was enrolled in three groups (chitosan 500 mg BD, lifestyle modification, and chitosan 500 mg BD and lifestyle modification). Data were analyzed using “t”-test and ANOVA. Results: There is a reduction in BMI in all the three groups. However, when we combined chitosan and lifestyle modification, there is pronounced reduction in BMI, which is statistically significant (p<0.0001). Conclusions: Chitosan and lifestyle modification have more pronounced effect on reduction on BMI as compared to monotherapy alone.
Authors and Affiliations
VASUNDHARA BHOPLE , DEEPAK BHOSLE
THERMODYNAMIC AND KINETIC STUDIES FOR THE BINDING OF LEAD ION BY CHELATING WITH THEOPHYLLINE 1,3-DIMETHYLXANTHINE (THERAPY DRUG)
Objective: Chelating therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body; chelating agents detoxify heavy metals and toxins, converting them to inactiv...
ISOLATION AND IDENTIFICATION OF PHYTOSTEROLS FROM BIGNONIA VENUSTA (L.)
Objective: To isolate phytosterols from Bignonia venusta (L.) and its antimicrobial activity.Introduction: B. venusta is an important medicinal plant known for its vast potential. It is a valuable plant which is commonly...
DIABETES MELLITUS TREATMENT: A RAPID REVIEW ON INNOVATIVE THERAPIES
Diabetes mellitus is a chronic and metabolic disorder which results from defects in a section of insulin, action of insulin, or both. Primarily drugs are used to control the symptoms and save life. Secondary aims are to...
OPTIMIZATION, ISOLATION AND CHARACTERIZATION OF BIOACTIVE COMPOUNDS FROM STREPTOMYCES LAVENDULOCOLOR VHB-9
Objectives: Optimization, isolation, and characterization of bioactive compounds from Streptomyces lavendulocolor VHB-9 isolated from granite mines of Mudigonda village of Khammam district of Telangana state.Methods: The...
COCRYSTALLIZATION ACYCLOVIR-SUCCINIC ACID USING SOLVENT EVAPORATION METHODS
Objective : The aim of this research is to prepare and characterize cocrystals of acyclovir through cocrystallization of acyclovir – succinic acid (AS) to improve the physical properties of the drug.  Methods : AS coc...