To Compare the Efficacy of Midazolam and Triclofos as Oral Premedicant in Paediatric Patients

Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2019, Vol 6, Issue 2

Abstract

Context: The primary goals of premedication in children are to facilitate a smooth separation from the parents and to ease the induction of anesthesia. Aims: To compare the efficacy of midazolam and triclofos when given orally as premedicants in children. Material and methods: 50 patients aged 2-6 years of ASA I & II were divided randomly into two groups equally. Group M received syrup midazolam, 0.5 mg kg-1 and group T received syrup triclofos 75 mg kg-1, orally as premedication. Level of sedation and behavior [1,3] at the time of separation from parents and during mask acceptance [1,3]. Statistical analysis: Unpaired t-test was used for statistical analysis. p-value <0.05 is significant. Results: In group-M 56% and 40% patients while in group-T 24% and 8% patients achieved a sedation score of 4 and 5 respectively (p<0.05). In group-T 64% and 24% while in group-M 8% and 12% patients achieved a behavior score of 1 and 2 respectively at the time of separation from parents (p<0.05). In group-M 68% and in group-T 24% patients achieved a mask acceptance score of 4 (p<0.05). Conclusion: Oral midazolam 0.5 mg kg-1 was better in terms of level of sedation and behavior at the time of mask acceptance whereas, triclofos 75 mg kg-1 was better in terms of behavior at the time of separation from parents in paediatric age group 2 to 6 years. Hence, midazolam was found to be superior to triclofos.

Authors and Affiliations

Anubhav Sardana

Keywords

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  • EP ID EP619282
  • DOI 10.21088/ijaa.2349.8471.6219.27
  • Views 70
  • Downloads 0

How To Cite

Anubhav Sardana (2019). To Compare the Efficacy of Midazolam and Triclofos as Oral Premedicant in Paediatric Patients. Indian Journal of Anesthesia and Analgesia, 6(2), 543-546. https://europub.co.uk/articles/-A-619282