To compare the efficacy of Outpatient Blood Pressure record with Ambulatory Blood Pressure Monitoring (ABPM) in the clinical follow up of hypertensive patients on antihypertensive therapy
Journal Title: The Journal of Medical Research - Year 2018, Vol 4, Issue 5
Abstract
Introduction: Optimal BP control is requiring a smooth reduction in the 24-hour BP profile. There are multiple components of BP like day time mean, night time mean, 24 hrs mean, blood pressure variability, day- night difference and it is still not clear which particular component is the best predictor of prognosis. There a need to define the control in our population as very few studies exist in our population. Material and Methods: Study population- This matched-paired, cross-over study was performed in a tertiary care cardiac centre in a metro city of India from September 2014 to July 2016. Study protocol- Subjects were advised to take anti-hypertensive drugs at 0600 hrs and rest at any time of the day After baseline BP at 1st visit, OPD BP readings were taken at 1, 3 and 6 months. It was compared with ABPM done at 1 and 6 months. Oscillometric (Space Labs 90202; Spacelabs, Inc., Redmond, WA) ambulatory blood pressure monitor was used for 24 hr ABPM measurements. This device took BP reading every 30 minutes from 6:00 am to 10:00 pm and at 60-minute intervals in the night (from 10:00 pm to 6:00 am). OPD BP, smoking, exercise, body weight, drug compliance, and adverse effects were assessed at each OPD visit. Statistical analyses: Data expressed as the mean ±SD. Comparisons of (1) the OPD mean systolic and diastolic BP at start, one month, three months and six months, (2) OPD and ABPM at one and six months (3) daytime and nighttime systolic and diastolic BP of ABPM, and, (4) change in MAP between group A and group B was made using a paired sampled t-test. A value of 2-tailed P < 0.05 was considered statistically significant. Results: The present study included 51 patients who were on regular follow up from medical OPD of a tertiary care centre. Two patients were lost to follow up. In our study the Mean systolic OPD BP was 137.33 ± 11.82 with corresponding ABPM 123.92 ± 13.17 which is statistically significant. Also, when OPD and ABPM mean systolic are compared at 6 months the p value is statistically significant. When similar comparison is done for diastolic blood pressure p value at one month is not statistically significant but at six months is significant. Conclusion: OPD systolic BP at start with OPD systolic BP at one, three and six months the difference was statistically significant. Similar results were found for diastolic and MAP except at one month.
Authors and Affiliations
Munish Sharma, Anupam Pandit
Keywords
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- EP ID EP531996
- DOI 10.31254/jmr.2018.4503
- Views 137
- Downloads 0
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To compare the efficacy of Outpatient Blood Pressure record with Ambulatory Blood Pressure Monitoring (ABPM) in the clinical follow up of hypertensive patients on antihypertensive therapy
Introduction: Optimal BP control is requiring a smooth reduction in the 24-hour BP profile. There are multiple components of BP like day time mean, night time mean, 24 hrs mean, blood pressure variability, day- night dif...