To Compare the Efficacy of Pre-Operative Prophylactic Antibiotic Therapy Versus Routine Post-Operative Antibiotics in Routine Gynecological Surgeries
Journal Title: Indian Journal of Obstetrics and Gynecology - Year 2018, Vol 6, Issue 3
Abstract
Background: Cesarean section and hysterectomy are most commonly performed operations in obstetrics and gynecology. The most common complication associated with hysterectomy is infection. Single dose preoperative antibiotic prophylactic therapy also reduces cost, potential toxicity, post operative infection and risk of duration of hospitalization, colonization with resistant organisms hence, the current study is undertaken to evaluate a efficacy of single dose of preoperative antibiotic prophylaxis versus routine postoperative antibiotic therapy in gynecological surgeries. Method: 100 patients admitted and undergoing elective Gynecological surgeries like vaginal hysterectomy, abdominal hysterectomy and laparotomies in the department of Obstetric and Gynecology were enrolled in the study as per selection criteria. They were randomly assigned as group I and group II after obtaining informed consent. Result: The incidence of febrile morbidity in group I was 5% and 8.33% in group II and was statistically insignificant. Incidence of infectious febrile morbidity in group I is 1.66 and 3.33% in group II. 3.33% patients in group I and 5% patients in group II had non-specific pyrexia. The incidence of postoperative infectious morbidity in group I was 5% and in group II was 10%. Prolonged postoperative stay (>10 days) observed in 10% of patients in group I and 21.66% patients in group II. Conclusion: Single dose antibiotic prophylaxis is equally effective in preventing post operative (respiratory/ urinary/ pelvic) infections and surgical site infection. As far as safety is concerned, single dose antibiotic is safer than routine antibiotic for prolonged period. Single dose antibiotic prophylaxis is more cost effective than routine antibiotic for prolonged period.
Authors and Affiliations
Shailesh B. Patil
Keywords
Related Articles
- EP ID EP549893
- DOI 10.21088/ijog.2321.1636.6318.19
- Views 61
- Downloads 0
Maternal Age and Pregnancy Outcome
Background: Maternal age plays important role in pregnancy outcome. Aim: To study various pregnancy outcomes in different age group. Materials and Methods: It is a retrospective study in which records were studied by fol...
A Clinical Study on Amniotic Fluid Index and Perinatal Outcome
Background and Aim: The aim of antepartum fetal surveillance is to identify fetus at increased risk of harm. Amniotic fluid volume has been proved an indirect measure of fetoplacental function and hence the estimation of...
The Prevalence of Symptomatic & Asymptomatic Bacterial Vaginosis and Its Treatment in Managing Preterm and Threatened Preterm Deliveries
Background: 8-10% pregnancies end in preterm labour or threatened preterm labour which has maternal and foetal complications just due to infections such as bacterial vaginosis, which can be identified by simple tests lik...
Study of Feto-Maternal Outcome in Pregnant Females with Infective Hepatitis
Objectives: To study the clinical course, morbidity and mortality in the pregnant patients affected by the disease, To study the effect of Infective hepatitis on outcome of pregnancy. Material & Method: The present study...
The Effect of Hyoscine Butylbromide and Drotaverin on First Stage of Labor
Active management of labor is a part and parcel of modern obstetrics. Various drugs have been tried to hasten cervical dilatation so that problems and hazards of prolonged labor both for the mother and fetus are minimize...