To compare the role of i.v clonidine, MgSO4 and esmolol in attenuating hemodynamic responses following laryngoscopy and intubation and on blood loss in patients undergoing endoscopic sinus surgeriessurgeries
Journal Title: PARIPEX-Indian Journal of Research - Year 2017, Vol 6, Issue 8
Abstract
Aim: The aim of our study was to compare the role of i.v clonidine, MgSO4 and esmolol in attenuating hemodynamic responses following laryngoscopy and intubation, in maintaining peri-operative HR and MAP, and on blood loss in patients undergoing endoscopic sinus surgeries(ESS). Material & method : 80 normotensive patients, undergoing ESS, ASA I and II physical status were divided into 4 groups of 20 patients each. In group I patients received 10 ml normal saline followed by same volume normal saline infusion, in group II patients received 2μg/kg clonidine in 10 ml NS bolus 5 min before induction followed by 1μg/kg/hr infusion, group III patients received 30 mg/kg magnesium sulphate in 10 ml NS bolus just before induction followed by 10mg/kg/hr infusion and in group IV patients received 1mg/kg esmolol in 10 ml NS bolus just before induction followed by 0.6mg/kg/hr infusion. Result and conclusion: Clonidine and esmolol are better in controlling the rise in HR and MAP following laryngoscopy and intubation.The amount of bleeding and surgeon satisfaction score were also better in clonidine and esmolol group compared to MgSO4 and control group.
Authors and Affiliations
Dr Deepak Kumar, Dr Peeru Singh, Dr Zara Wani
Keywords
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