To compare the safety, efficacy and tolerance of intravaginal PGE 1 tab with intravaginal PGE 2 gel in induction of labour
Journal Title: Panacea Journal of Medical Sciences - Year 2017, Vol 7, Issue 1
Abstract
Induction of labour is an intervention designed to artificially initiate uterine contractions leading to progressive dilatation and effacement of the cervix and birth of the baby. There are various methods of induction of labour. Locally applied PGs have been thought to be most physiological in initiating the process of labour by promoting both cervical ripening and myometrial contraction the present study was carried out to compare the efficacy, safety and tolerance of intravaginal misoprostol (PGE1) tablets with intravaginal dinoprostone (PGE2) gel for cervical ripening and labour induction at term. A randomized control study was carried out. Two hundred women with unfavorable cervix were randomly allocated in two groups of 100 women each for misoprostol group and dinoprostone group respectively. Success of induction, mean induction to delivery interval, mode of delivery, maternal complications and Apgar score were analyzed. Statistical analysis was done by unpaired one tailed test and chi square test. The mean induction to active phase of labour was 11.61 hrs in misoprostol group and 14:29 hrs in dinoprostone group, mean induction to delivery interval was 15:07 hrs in misoprostol group and 18.11hrs in dinoprostone group. 86% of women in misoprostol group delivered vaginally as compared to 75% in dinoprostone group. No significant difference in the maternal and fetal outcome w was noted. Intravaginal tablet misoprostol 25 mcg every 6hrs for maximum of 100 mcg is an effective, safe, tolerable, low cost and simple method of cervical ripening and induction of labour at term.
Authors and Affiliations
Rakhi Rai, Sulabha Joshi
Keywords
Related Articles
- EP ID EP316213
- DOI 10.18231/2348-7682.2017.0009
- Views 105
- Downloads 0
Breast Hamartoma: Breast within Breast Sign
Breast hamartoma is one of the rare benign lesions described. A varied histopathological type of hamartoma has been described under this heading. However the imaging findings are unable to distinguish these histopatholog...
Evaluation of results of combined Phacoemulsification and Pars Plana Vitrectomy
The cataract and vitreoretinal disease commonly coexist in the elderly population and the presence of cataract hampers visualization in vitreoretinal surgery, thus concurrent removal of cataract helps in better visualiza...
Use of smart phone for measuring shoulder rotational range of motion in patients with frozen shoulder: A comparative study
Assessment of shoulder range of motion in patients with frozen shoulder is important aspect for physiotherapist for documentation and to check progression in disease. From long time, goniometer is used as gold standard m...
Comparison of 90-90 passive hamstring stretching technique plus knee to chest position with 90-90 passive hamstring stretching alone in normal healthy individuals of age 18 to 25 years
Hamstring flexibility plays an important role in physical fitness Hamstring tightness is determined by knee extension deficit Passive stretching is simple and found effective to improve muscle flexibility In clinical set...
Childhood obesity: Not so common for adolescents in an urban slum
Childhood obesity is emerging as a major health problem among early adolescent school children. The present study is a cross sectional, questionnaire based study carried out among 220 early adolescent school children in...