To evaluate the effect of 0.5% intracameral pilocarpine on intraocular pressure after topical phacoemulsification
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Background: Elevated intraocular pressure is the most frequent postoperative complication demanding treatment following phacoemulsification.So this study has been carried out to evaluate the effect of 0.5% intracameral pilocarpine on intraocular pressure changes after topical phacoemulsification and to compare it with an age matched group of patients undergoing topical phacoemulsification without pilocarpine. The aim was to see if intraoperative use of 0.5% intracameral pilocarpine will prevent the post operative spike of intraocular pressure following phacoemulsification. Methods: Patients were randomly divided into two groups: group 1 (50 eyes) with 0.5% intracameral pilocarpine after completing phacoemulsification under topical anaesthesia and group 2 (50 eyes) without 0.5% intracameral pilocarpine. Every alternate patient was assigned to a different group to rule out any selection bias. Baseline and postoperative intraocular pressure was recorded with a non contact tonometer in both groups. Data collected was statistically analyzed. Results: This study recruited 100 patients of cataract having Nuclear Sclerosis 2+/3+. Patients were grouped as: Group 1: 50 eyes with 0.5% intracameral pilocarpine after phacoemulsification under topical anaesthesia.. Group 2: 50 eyes without 0.5% intracameral pilocarpine after phacoemulsification under topical anaesthesia. There was significant rise in intraocular pressure noticed in both groups at 4 hours and 8 hours postoperatively. However intraocular pressure returned to preoperative levels within 24 hrs postoperatively. There was significant reduction of IOP noted postoperatively at 4hrly and 8 hrly intervals in group 1 in which 0.5% intracameral pilocarpine was used as compared to group 2 after phacoemulsification. Conclusion: Use of 0.5% intracameral pilocarpine after topical phacoemulsification significantly reduces intraocular pressure for 08 hrs postoperatively.There is no significant difference in reduction of intraocular pressure 24hrs postoperatively in both groups.
Authors and Affiliations
Dr Amit Arora
Keywords
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- EP ID EP369065
- DOI 10.9790/0853-1703045961.
- Views 78
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