To evaluate the influence of inhaled bronchodilator therapy on spirometric test variables in obese and non-obese asthmatics
Journal Title: Journal of Medical and Scientific Research - Year 2015, Vol 3, Issue 4
Abstract
In India, the prevalence of overweight individuals is reported to be between 20-40% in various studies, with over 5-10% being obese. Obesity acts as a risk factor for asthma through various mechanisms and it also reduces the spirometric variables as well as total lung capacity and functional residual capacity. Forced expiratory volume in one second (FEV1) was done on 100 patients in tertiary care hospital using RMS Helios 401 electronic spirometer, by Recorders and Medicare Systems Pvt. Ltd. All the statistical analysis was done using SPSS, Ver. 17.0, (IBM, Chicago, Illinois and student unpaired T-test and analysis of variance (ANOVA) test was used for estimating results. 59 were males and 41were females, of the 59 males, 29 were obese and 30 were non-obese and of the 41 females 20 were obese and 21 were non-obese. There was highly significant difference found in the spirometric variables in obese and non-obese asthmatics. There is significant amount of reversibility (% change) after inhalation of short acting beta-2 agonist in non-obese group as compared with obese group with mean percentage change in non-obese group being 16.20% and obese group 13.58%. p value 0.002(p<0.05). The amount of reversibility (mean % change) was found to be more for controlled asthmatic groups (16.88%) as compared with partly controlled asthmatics (14.84%) and uncontrolled asthmatic groups(12.78%) p value 0.001(p<0.05). To conclude, it can be said that age does not have any significant influence on the levels of asthma control in both obese and non-obese asthmatics. Obesity has a significant influence on various spirometric variables.
Authors and Affiliations
Latha S, Nandan P, Avinash C, Mohit C, Qureshi A
Keywords
Related Articles
- EP ID EP607532
- DOI 10.17727/JMSR.2015/3-032
- Views 95
- Downloads 0
Pulsed radiofrequency ablation of median nerve in a patient with soft tissue sarcoma
Pulsed radiofrequency (PRF) is a novel therapeutic modality with many potential applications in pain management. A 14-year-old male patient with soft tissue sarcoma of right hand in the first and second interdigital clef...
Laparoscopic appendectomy in a patient of 32 weeks gestational age
Most common non-obstetrical surgical emergency complicating pregnancy is acute appendicitis. Laparoscopic surgery for appendectomy in pregnant women is proving to be safe in all trimesters as surgical skills have increas...
Screening and prevention of cervical cancers
Cervical cancer in India ranks as the 2nd most frequent cancer among women and the 2nd most frequent cancer among women between 15 and 44 years of age. As per National Cancer Registry, crude incidence and mortality rate...
Utility of immunohistochemistry in the diagnosis of bone tumors
Immunohistochemistry (IHC) plays an important role in the diagnosis of some bone tumors, especially in the differential diagnosis of primary from metastatic non-osseous tumors and in the categorization of small-round-blu...
Analysis of vitamin B12 and D deficiency and the effect of supplementation on patients at tertiary care hospital
Vitamins are essential organic compounds for the body and the study aims to understand the extent of deficiency present among the patients tested for deficiency and the effect of supplementation. Our study also aims in u...