To investigate the relation between total IgE levels and spirometery in asthma
Journal Title: IP Indian Journal of Immunology and Respiratory Medicine - Year 2018, Vol 3, Issue 1
Abstract
Background The present study was carried out to observe the relationship between total IgE levels and spirometry in asthmaMethodology The study was carried out in KBN Hospital Respiratory clinics OPD Total 100 patients with asthma symptoms were taken in study with no other systemic disorder Serum IgE levels were measured by ELISA technique value gt100IUml were taken as positive spirometry was conducted on all patient by using USB spirometer according to ATS standard data were analyzedResults We included 100 patients of asthma in our study serum IgE levels varied markedly showing IgE levels90 50 gt100IUl and 40 gt400IUl of IgE levels were more than 100IUl and 10 were less than 100IUl spirometery showed 60 were having FEV1FVCgt80 and 40 were lt80 lt6015 and 258060Conclusions The mean percentage of predictive value of FEV1FVC is significantly low in high IgE levels It was concluded that serum IgE levels increase as the severity of airflow obstruction increasesKeywords FEV1Forced expiratory volume FVCForced vital capacity ImmunoglobinE
Authors and Affiliations
Gousuddin Arif, Abida Farheen
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