TO STUDY AND COMPARE THE ANTIOBIOTIC SENSITIVITY PATTERN OF ORGANISMS INVOLVED IN INFECTIONS IN PATIENTS WITH SEVERE ACUTE MALNUTRITION (SAM).
Journal Title: PARIPEX-Indian Journal of Research - Year 2017, Vol 6, Issue 1
Abstract
Severe acute malnutrition (SAM) defined by a very low weight for height (below -3z scores of the median WHO growth standards), is a devastating public health problem of epidemic proportions. Diminished immune functions render undernourished patients more susceptible to multiple infections and many severely malnourished children die from delay inappropriate treatment. This study was undertaken to study the antibiotic senstitivity pattern among organisms causing infections in patients with severe acute malnutrition so as to aid in developing a local antibiogram. MATERIAL AND METHODS : In this study 72 children aged 6 months-60 months, classified as SAM children as per WHO criteria were included and their blood cultures and antibiotic sensitivity were studied and analysed. RESULTS AND CONCLUSION : Our study shows that infections in patients with severe acute malnutrition is a common occurrence with gram negative organisms being more than gram positive organisms with E.coli being the most common culprit. As per our study, we recommended that the patients suffering with SAM with associated comorbidities, with high suspicion of sepsis should be started empirically with ceftriaxone or cefotaxime . In case of non improvement , or subtle response vancomycin (if gram positive suspected) or Amikacin (if Gram negative sepsis is suspected) may be added as an additional drug, finally until the blood culture and sensitivity results for the organisms are available.
Authors and Affiliations
Dr raja goswami, Dr Avyact Agarwal, Dr M L Burman
Keywords
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