To Study Red Cell Indices and Platelet Indices in Acute Coronary Syndrome
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 2
Abstract
Introduction: Platelets play a key role in the development and progression of cardiovascular disease. Patient with deranged red cell indices and platelet volume indices can be easily identified during routine hematological analysis and could benefit from preventive measures. Current research aimed to study severity and extent of myocardial injury in patients of Acute coronory syndrome based on echo cardiography and its correlation with red cell indices and platelet indices and to record the correlation of red cell indices and platelet indices with mortality in patients of Acute coronory syndrome. Material and Methods: A total of 137 patients admitted in medicine intensive care unit were included. All the records were recorded by using structured schedule (Case Report Form) and entered in Microsoft Excel Sheet. Platelet indices and red cell indices were measured in all patients. Global registry of acute coronary events (GRACE) score was used for assessment of the risk of death. Extent of myocardial injury was assessed by left ventricular systolic dysfunction on basis of 2D ECHO. Results: Blood indices –MPV (10.34 ±1.28), PLCR (38.79 ±10.49) were found to be significantly higher (P<0.0001) in STEMI patient as compared with NSTEMI (MPV 9.52 ±1.13, PLCR33.15 ±8.83) and UA (MPV9.21 ±1.09 PLCR 30.92±7.82). RDW (56.05± 15.16) was significantly higher (p<0.05) in moderately reduced ejection fraction as compared with mildly reduced (RDW50.37±6.63) and normal (RDW50.24±6.63). MPV (10.67±1.13) PDW (16.23±0.59) PLCR (39.66±9.67) were signicantly higher (P<0.001, P<0.001 P<0.016 respectively) in high risk mortality group as compared to moderate (MPV10.1±1.23, PDW 15.91±0.44 PLCR36.78±10.37) and low risk group (MPV9.45±1.21 PDW15.89±0.45 PLCR33.11±9.31). Conclusions: MPV, PDW and PLCR may be considered prognostic markers for acute coronary syndrome.RDW can be used to assess severity of myocardial injury.
Authors and Affiliations
A. Walke, S. S. Nelson
Keywords
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