TO STUDY RETROGRADE AUTOLOGUS PRIMING (RAP) AS AN IMPORTANT BLOOD CONSERVATION MODALITY AND ITS ROLE IN POST OPERATIVE OUTCOME - A STUDY OF 200 CASES IN MADRAS MEDICAL COLLEGE, CHENNAI.
Journal Title: GJRA-Global Journal For Research Analysis - Year 2018, Vol 7, Issue 11
Abstract
AIMS AND OBJECTIVES : To study the effect of retrograde autologous priming techniques on transfusion requirements and outcome in CABG patients. 1. The effect on peri-operative transfusion requirements. 2. The effect on post-operative morbidity. 3. The effect on duration of post operative stay. MATERIALS AND METHODS : We analysed the patient details retrospectively using the charts as well as our clinical clinical workstation. Categorical data were expressed as frequency and percentage. Categorical data were expressed as frequency and percentage. Continuous variable expressed as mean ± standard deviation. Signicant differences between proportions determined by Chi-squared analysis or Fischer's exact test. All analysis were carried out using Statistical Package for Social Service version 16(SPSS Inc.,Chicago, IL, USA). Probablity values p<0.05 were considered signicant. RESULTS: We had a total of 200 patients in our series from 2014-15. Coronary artery disease is more common in males 83% of our study group. Commonly seen in Diabetics(60%), hypertensives(62%) and smokers(30%), their respective percentages in the study population. Analysing Retrograde autologus priming as a blood conservation modality we were able to derive at a reduction in hemodilution, transfusion rates, creatnine and lactate levels, period of stay but were not able to exhibit statistical signicance. The factors like intra operative hemodilution(p=0.039) and transfusion(p=0.050). Post operative creatnine levels(p=0.026) and Stay in the ICU(p=0.014) were signicant. CONCLUSION: We were able to establish Retrograde Autologus Priming as one of the blood conservation modalities. As in other literature, our study also suggests that Retrograde Autologus Priming of cardiopulmonary bypass circuit as an effective blood conservation modality. There is a signicant reduction in the total transfusion rates of patients in the Retrograde Autologus Priming group in the overall study. Though only the intra op transfusion rates and post operative critical care stay were deemed statistically signicant, in this retrograde study, It is promising to note and could get more gratifying results if there could be a prospective study with strict transfusion triggers.
Authors and Affiliations
Dr P Amirtharaj
Keywords
Related Articles
- EP ID EP499730
- DOI -
- Views 100
- Downloads 0
RISK FACTORS AFFECTING SYMPTOMS OF DEPRESSION IN MOTHERS OF CHILDREN WITH LEUKEMIA
The prevalence of depression in mothers of children with leukemia undergoing chemotherapy was as high as 91%, while the risk factors are still unclear. To analyze the risk factors for symptoms of depression in mothers of...
UPPER GASTROINTESTINAL TRACT ENDOSCOPIC BIOPSIES.
Introduction: Upper GI Upper gastrointestinal tract is an important site for wide variety of lesions especially malignant tumors. Endoscopy in combination with endoscopic biopsy plays an important role in the diagnosis o...
Implementation of Mahatma Gandhi’s Ideology in Self Sustained Health Development of Rural Adult Girls
Mahatma Gandhi had a vision of India with self-sufficient and self reliant villages. Nutritionists can do a lot by objectively thinking, planning and implementing nutritional education programs for rural people. Rural ad...
Wilckodontics- Bridging Orthodontics and Periodontics
Achieving success in orthodontic therapy for adults is clinically challenging and lengthened in time due to the cease of dentoalveolar development. Additively; aplastic, narrow, less vascular periodontal membrane and alv...
Experimental Investigation of Waste Foundry Sand on Strength Properties of Plain Concrete and Comparison With Binary Blended Concrete
An acute shortage of river sand which is generally used as a fine aggregate in concrete has been affecting the construction sector. The scarcity has led to the skyrocketing price of sand, escalating construction costs. T...