TO STUDY THE ASSESSMENT OF LIPID ABNORMALITIES IN PATIENTS SUFFERING FROM GALLSTONES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 21
Abstract
BACKGROUND 80 percent of gallstones are made of cholesterol, whereas 20 percent of gallstones are made of calcium salts and bilirubin. Gallstone diseases being common disorders might have an association with abnormal lipids. Aims and Objectives- This study is done to assess the lipid abnormalities in patients suffering from gallstone diseases. MATERIALS AND METHODS The is a case control study, the sample size was taken for convenience during the study, and was carried out in the Department of Biochemistry among the healthy individuals and patients of gallstones attending the OPD of General Surgery, Rama Medical College Hospital and Research Centre, Mandhana, Kanpur (UP). The gallstones were collected after cholecystectomy. 5 mL of blood sample was collected after overnight fasting from each of the participants to measure the serum lipid parameters. Student’s independent ttest was used to examine the degree of significance. P values less than 0.05 was considered significant. Limitations- Since the calculated sample size was too high and thereby not feasible to include in this limited period of study, we had to limit the sample size for convenience. RESULTS Levels of serum triglyceride and levels of VLDL are statistically significant (p < 0.05), while the levels of serum cholesterol, HDL and LDL are not statistically significant (p > 0.05). The results are depicted in different tables to compare the groups individually. CONCLUSION Although, this small sample size study concluded that there is correlation between presence of gallstones and TGs as well as VLDL, but a larger sample size study is required to further strengthen these risk factors.
Authors and Affiliations
Mahesh Gupta, Vivek Singh, Pooja Gupta, Preety Gupta
Keywords
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- EP ID EP431632
- DOI 10.14260/jemds/2018/579
- Views 88
- Downloads 0
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