To Study the Clinico-Pathological Profile and Radiological Characteristics in Patients with Liver Abscess”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
: Background: Liver abscess is a serious problem especially in tropical regions like the Indian subcontinent. Itsignificant mortality and also poses diagnostic and therapeutic challenges. Present study describes the clinical, pathological and radiological profile of liver abscess patients attending the tertiary care hospital during the study period. Aims & Objectives: To Study a Clinico-Pathological profileand Radiological Characteristics of liver abscess patients.Methods:This is Prospective study was carried out in the Department of Medicine, G.R. Medical College and J.A. Group of Hospitals, Gwalior between January 2016 to August 2017 Total of 120 cases of liver abscess were included in the study.Statistical Analysis: All the data analysis was done using IBMSPSS version 20 software. Data is expressed as percentage and mean ± SD. Student t test and analysis of variance was used to tabulate the data. P value of <0.05 is considered as significant.Results:The age of patients ranged from 16 to 82 years. Out of 120 patients, 107 were males and 13 were females with a Male to female ratio of 8.23:1. The most common presentation of Liver Abscess was fever,abdomen pain & malaise which were present in 94.2%, 90.8%& 90 % in our patients respectively and signs like tender hepatomegaly and pallor were 75% and 73.33% respectively. Fever with chills and abdomen were most common in 21-40 age group and Nausea, weight loss and Anorexia were most common in 41-60 age groups. The right lobe(80%) was most commonly involved. Abscess was most commonly solitary (57.5%). Maximum patients had abscess size between 100-300mL (75%). In relation to aetiology, amoebicliver abscess was the most common type. Investigations found that 64 cases (53.3%) were amoebic in origin, 56 cases (46.7 %)were pyogenic in origin.Pyogenic liver abscess 44 (78.5%) was generally multiple in type.Conclusion:In present study most common symptoms like fever, abdomen pain, malaise wheretender hepatomegaly& pallor was most common signs. In younger age groups fever with chills and abdomen pain was most common due to good immunity where in older age groups non-specific symptoms were most common. Most common aetiology associated with abscess was amoebic which is solitary in type and maximum size belong to more than 100 mL in radiological characteristic where Pyogenic liver abscess is generally multiple in type and smaller size in radiological appearance.
Authors and Affiliations
Arya D, Singh N1, Jatav O. P, Trikha S1, Shah N, Singhal P
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