To Study the Effect of Pre-Emptive Doses of Gabapentin for Postoperative Analgesia in Patients Undergoing Surgery under General Anaesthesia
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 11
Abstract
Abstract: Postoperative period is very crucial from recovery point of view. For fast and smooth recovery, postoperative period should be free of complications especially pain. Multimodal analgesia is quite effective and has lesser side effects compared to the use of single analgesic agent.Our hypothesis is that pre-emptively given oral gabapentin reduces postoperative pain in patients scheduled for surgery under general anaesthesia. This randomized control study was conducted on 60 patients of ASA grade 1 and 2 after taking ethics committee approval. Patients were divided into two groups. In Group G (n=30), patients received 600 mg of Gabapentin orally one and half hours prior to surgery.and Group C (n=30), patients received Placebo orally one and half hours prior to surgery. Diastolic, systolic and mean blood pressure, heart rate were measured throughout the procedure. Time of rescue analgesia and VAS score was recorded postoperatively. Oral gabapentin given pre-emptively provides postoperative analgesia. Mean duration of first rescue analgesia in group G was 36.28±9.98 that was significantly low (p<0.05) in comparison to group C 57.34±18.31. Time of second rescue analgesia in group G and C was 104.44±31.02 and 123.00±40.06 respectively. oral gabapentin given pre-emptively reduces postoperative pain in patients scheduled for surgery under general anaesthesia.
Authors and Affiliations
Anju Gautam, Nidhi Sharma, Ritu Masar, Neelima Tandon
Keywords
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