TO STUDY THE EFFICACY OF ORAL MIDAZOLAM AS A PRE-MEDICATION FOR CHILDREN POSTED FOR GENERAL ANAESTHESIA.
Journal Title: International Journal of Advanced Research (IJAR) - Year 2018, Vol 6, Issue 2
Abstract
Introduction: The major objectives of preanesthetic medication are to decrease the stress response with preservation of hemodynamic parameters, facilitate anaesthesia induction and produce amnesia. Preoperative anxiety is a common phenomenon in children. Midazolam is commonly used in children and has been demonstrated to be a very good sedative, anxiolytic and amnesic premedicant. Midazolam is absorbed rapidly and completely after oral administration. Methods: Aim of the study was to study the effectiveness of oral Midazolam as premedication of paediatric patients undergoing surgery under general anaesthesia with respect to: Ease of separation from parents, degree of sedation achieved (sedation score) preoperatively and postoperatively and patient?s co-operation for venipuncture. Material and method: The study was carried out in department of anaesthesiology JNMC and AVBRH Savangi, Meghe, Wardha, during 2016-2018 after taking prior permission from institutional ethical committee. It comprised of 60 subjects. They were randomly allocated to 2 groups. Group A - patients received 0.5mg/kg body weight oral Midazolam, Group B ? patients received 1.0mg/kg body weight oral Midazolam Results: 1 mg/kg body weight dose gave better results than 0.5mg/kg body weight dose in terms of ease of separation from parents and co-operation for venepuncture. Conclusion: 0.5mg/kg and 1mg/kg body weight doses of oral Midazolam can be safely administered as premedication to paediatric patients but 1 mg/kg body weight dose is more effective as a pre medication for children posted for General Anaesthesia.
Authors and Affiliations
Karuna Taksande
GC-MS ANALYSIS OF BIOACTIVE COMPOUNDS AND ANTIMICROBIAL ACTIVITY OF CRYPTOCOCCUS RAJASTHANENSIS KY627764 ISOLATED FROM BOMBYX MORI GUT MICROFLORA.
The insect gut microflora acts as a large reservoir of bioactive natural products as a diversity of resident microflora is found to be symbiotically associated with the insect. The present study reports the bioactive che...
LEUKOARAIOSIS AND DEPRESSION: LINKS BETWEEN THE RADIOLOGICAL ENTITY AND THE DEPRESSIVE SYMPTOMATOLOGY.
Leukoaraiosis is a purely descriptive term for a radiological image, which describe confluent white matter abnormalities, detected by computed tomography (CT) or magnetic resonance imaging (MRI). The clinical presentatio...
COMPARATIVE EVALUATION OF MICROLEAKAGE AND COMPRESSIVE STRENGTH OF GLASS IONOMER CEMENT TYPE IX, ZIRCONOMER IMPROVED AND CENTION N - AN IN VITRO STUDY.
Context:Restorative dentistry is a blend of art and science. Newer restorative materials like Cention N and Zirconomer Improved are giving a challenge to conventional restorative materials. Aims: To evaluate and compare...
MEASURING STUDENT SATISFACTION THROUGH SERVQUAL: EMPIRICAL STUDY AT BINAWAN UNIVERSITY.
This study aims to identify the student satisfaction through service quality in the higher education. The study used a descriptive approach involving 144 students from Binawan University. Data collection using questionna...
LEGAL PROTECTION AGAINST WOMEN AS VICTIM IN DOMESTIC VIOLENCE IN PAPUA: A HUMAN RIGHTS PERSPECTIVE.
The recognition, protection and human rights enforcement are legally guaranteed under various rules both in the constitution and in various organic laws. The research was conducted in Jayapura city, Papua Province, Indon...