To Study the Etiology and Predicting Scores of Patients with acute on chronic liver failure
Journal Title: Asian Pacific Journal of Health Sciences - Year 2018, Vol 5, Issue 4
Abstract
Aim: To study the aetiology, precipitating insults of patients presenting with acute on chronic liver failure and predictors of mortality of acute chronic liver failure. Methods: The prospective study was carried out in 100 patients admitted with acute on chronic liver failure for a period of 1 year in the Department of Medicine of Government medical college and Hospital, Jammu. Results: ACLF has a predominant male preponderance i.e 92 %. The mean age of patients presenting with ACLF was 45.39 ± 1.1 yrs. Among causes of chronic liver disease alcohol was commonest (79 %) followed by Alcohol + Hepatitis C (4.0 %) ,Alcohol + hepatitis B (1 %), Hepatitis B (1 %), Hepatitis C (3 %), NASH related (4 %) and Auto immune (5 %).Etiologyof acute precipitants included alcohol (43%) followed by Alcohol with Hepatitis B/C (9 %), alcohol with Hepatitis E (4%), alcohol with hepatitis E + Dengue (2%), Hepatitis E (8%), Hepatitis B (8 %) and Hepatitis C (6%) ,Hepatitis E + Leptospirosis (2%), leptospirosis (1%) and gastrointestinal bleed + others etiology (14%) were other causes of acute etiology in patients of acute on chronic liver failure. The mean SOFA, MELD and MDF scores were found to be better predictors of mortality. Conclusion: ACLF carries a high mortality rate. Alcohol was found to be the most common cause of chronic etiology of Chronic liver disease as well as acute insult. Scoring systems such as SOFA, MELD and MDF scores were considered to better predictors of mortality.
Authors and Affiliations
Rachit Magazine
Keywords
Related Articles
- EP ID EP517858
- DOI 10.21276/apjhs.2018.5.4.3
- Views 196
- Downloads 0
Clinical profile of patients with Drug resistant tuberculosis in Mumbai
Background: Tuberculosis is a global epidemic. Drug Resistant Tuberculosis (DR-TB) is a big blow to the National Tuberculosis Control Programme. Second line Anti TB drugs are expensive, toxic and weaker drugs than First...
The effects of facility-related factors on perinatal outcomes-a study of mothers attending antenatal services at public and non-public health facilities in Kisii County in the context of free maternity care services
Background: To improve perinatal outcomes, many countries in Sub-Saharan Africa are introducing universal access to maternal and newborn care. In June 2013the government of Kenya introduced free maternity services in al...
A Comparative Study between Intrathecal Clonidine and Neostigmine with Intrathecal Bupivacaine for lower abdominal surgeries
Background: Limited duration of time has been one of the main drawback of spinal anesthesia.To avoid this. adjuvants have been added to the local anesthetic agent and has proven benefits when used intrathecally. Aims and...
Efficacy of pregabalin in relieving acute postoperative pain- systemic Review & meta-analysis
Background: Pregabalin is used for postoperative pain management. Aims and Objectives: To evaluate efficacy of pregabalin in relieving acute postoperative pain. Materials and Methods: 650 studies were assessed, out of wh...
Azadirachta indica – Therapeutic Potential in Oro Dental Conditions
Azadirachta indica is an evergreen tree and has been known as a traditional medicinal plant in India. It has several beneficial properties and therapeutic effects like antibacterial, antifungal, antiviral, anthelmintican...