To Study the Pleural Fluid Bilirubin and Serum Bilirubin Ratio
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 1
Abstract
Many different conditions result in the accumulation of pleural fluid it may develop as a complication of many local & systemic diseases. Whether fluid accumulating in the pleural space is a transudate or an exudates, is determined by the widely used criteria proposed by Light et al i.e, 3 the pleural fluid to serum LDH & protein concentration ratio. Protein level of 3.0gm% and LDH level of 200 IU are used as dividing lines to separate transudation from exudate.5 This study has been conducted in the Department of Respiratory Medicine, Sri Aurobindo Medical College & PG Institute Indore (M.P.) From November 2016 to 30 April 2017. Total protein concentration (gram/dl) was measured by the “BIURET METHOD”. Total bilirubin concentration (mg/dl) measurement is based on “JENDRASSIK” & GROF METHOD” using diazotized acid with DMSO Sulphanilic acid as an activator for total bilirubin. Transudates, Exudates, Neoplastic Exudate, Non-Neoplastic Exudate Using a dividing line of 0.5 to separate transudates from exudates, 2 of 19 (10.5%) are falsely classified as having exudates while 17 of 19 (89.5%) are correctly classified as transudates. 2 of 14 (14.2%) Neoplastic exudates are incorrectly classified as a transudates and 12 (85.7 %) were correctly classified as exudates. In non neoplastic exudates are group 28 cases (87.5 %) out of 32 were correctly classified as exudates while 4 cases (12.5 %) were incorrectly classified as transudates. In this study 65 cases of pleural effusion were included, detail history and physical examination done and all cases were investigated including skia gram chest and routine biochemical and histopathological examination. Thoracocentesis was done and pleural fluid taken for biochemical and microscopic examination. According to criteria defined by Light et al, a pleural fluid is classified as exudates or transudates, pleural fluid is classified as exudates which match any one of the following criteria.
Authors and Affiliations
Ronak Jain, Pawan Kumar Shukla, Satish Motiwale, Ravi Dosi
Keywords
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