TO STUDY THE RELATIONSHIP BETWEEN MICROALBUMINURIA AND ISCHAEMIC HEART DISEASE IN NON-DIABETIC SUBJECTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 21
Abstract
BACKGROUND Microalbuminuria is known to be an independent risk factor for ischaemic heart disease in diabetics; however, its association in non-diabetics has not been addressed in detail. Aims and Objectives- To determine an independent association between microalbuminuria and IHD in non-diabetic subjects. MATERIALS AND METHODS A descriptive study was conducted in the Department of Medicine, Government Medical College, Kota in the year 2017-18. 100 non-diabetic subjects with IHD attending the outpatient clinic or admitted as inpatients in the Medicine wards of MBS Hospital, Government Medical College, Kota who were diagnosed as first time reported case of IHD on the basis of inclusion criteria (Electrocardiographic changes and Cardiac Enzyme Estimation and the Rose questionnaire) and exclusion criteria were included. Statistical Analysis- Data was compiled in MS Excel and checked for its completeness, correctness and then it was analysed. RESULTS In the present study, out of 100 cases, 72 cases were male and 28 cases were female. In our study, age group 56 - 65 years constituted 38% of the cases. Out of the 100 cases, 77 cases (77%) had microalbuminuria. Microalbuminuria is slightly higher in patients who presented with infarct pattern on ECG (78.2%) compared to ischaemia pattern (74.2%). Majority of patients had microalbuminuria level between 30 - 100 mg/day. 82.1% of females had microalbuminuria ≥ 30 mg/day compared to 75% of males in the present study. Hypertension was present in 58% of study subjects, in which females had higher percentage (Maleto-Females- 51.3% to 75%). Total 70 patients had history of smoking, out of which 77.1% (54 patients) had Microalbuminuria as compared to 75.8% non-smoker (22 patients) with Microalbuminuria. Mean Total Cholesterol, Mean Triglyceride and Mean LDL Cholesterol were higher in female in this study. Major dyslipidaemia was hypertriglyceridaemia in 34% of cases and low HDL in 31% of cases, which is typical Indian profile pattern. CONCLUSION Microalbuminuria is positively associated with Ischaemic Heart Disease in non-diabetic subjects and can be regarded as an important additional risk factor for Ischaemic Heart Disease.
Authors and Affiliations
Maneesh Kumar Varshney, Meena C. P, Girish Chandra Verma, Abdul Wahid Qureshi, Hemant Richhariya
Keywords
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- EP ID EP431623
- DOI 10.14260/jemds/2018/577
- Views 68
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