To Study The Status of LH: FSH Ratio in Obese And Non-Obese Patients of Polycystic Ovarian Syndrome.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Aim : To evaluate LH: FSH ratio in obese and non-obese patients of Polycystic Ovarian Syndrome(PCOS). Material and method:The study was conducted in Rajendra Institute of Medical Sciences, Ranchi. 102 patients were selected from patients visiting department of obstetrics and gynaecology, dermatology and medicine for complaint of menstrual irregularities, acne, hirsuitism, obesity and infertility. Ethical consent was taken. After proper counselling, informed consent of patients were taken. Fasting blood sample was taken on 3rd day of normal or induced menstrual cycle. Serum Luteinizing Hormone (LH) and Follicular stimulating hormone (FSH) was estimated with the help of chemiluminescence ABBOTT 1000 isr. Results: 78.43% had high level of LH. 72.5% had low FSH level. 74.5% had high LH: FSH ratio. 13.44% obese patient had high LH compared to 12.22% of normal weight patient. 5.29% of obese patient had low FSH level compared to 5.86% of normal weight patient. Similarly 2.67% of obese patient had high LH: FSH ratio. Conclusion: In PCOS women gonadotrophin ovarian axis is disturbed which is reflected by high LH and low FSH value. This hormonal imbalance leads to oligomenorrhoea, anovulation leading to infertility. Acne, hirshutism and obesity is seen in such patient of PCOS. Life style modification can help in curbing the disease to a great extent.
Authors and Affiliations
Laksman Lal, Atima Bharti, Arshi Perween
Keywords
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- EP ID EP588061
- DOI 10.9790/0853-1601012023
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