Tobacco Smoking and Lung Cancer Perception-changing facts
Journal Title: Sultan Qaboos University Medical Journal - Year 2013, Vol 13, Issue 3
Abstract
Tobacco smoking remains the most established cause of lung carcinogenesis and other disease processes. Over the last 50 years, tobacco refnement and the introduction of flters have brought a change in histology, and now adenocarcinoma has become the most prevalent subtype. Over the last decade, smoking also has emerged as a strong prognostic and predictive patient characteristic along with other variables. Tis article briefly reviews scientifc facts about tobacco, and the process and molecular pathways involved in lung carcinogenesis in smokers and never-smokers. Te evidence from randomised trials about tobacco smoking’s impact on lung cancer outcomes is also reviewed.
Authors and Affiliations
Muhammad Furrukh| Department of Medicine, Sultan Qaboos University Hospital, Muscat, Oman
Keywords
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