Toddler Presenting as Atypical Subacute Sclerosing Panencephalitis (With History of Measles Infection Affected at Less Than 6 Months of Age)
Journal Title: Hong Kong Journal of Paediatrics Research - Year 2018, Vol 1, Issue 1
Abstract
Background: Measles is caused by an RNA virus, paramyxoviruses affecting infants and toddlers commonly and Subacute sclerosing panencephalitis (SSPE) is a devastating “slow virus” brain disease resulting from persistent measles virus infection of neurons with a latency period of 8 to 10 years. Case characteristics: Here we report a case of measles affecting child of age group less than 6 months old and its progression into atypical SSPE with short latency period presenting clinically as progressive encephalopathy. Intervention: CSF measles antibodies were tested considering the spectrum of clinical scenario, neuroimaging findings and EEG findings. Outcome: Positive antibody titres in CSF for anti-measles antibody in a 18 months old child presenting as progressive encephalopathy.
Authors and Affiliations
Krishna Chaitanya, Dhanraj Dhanraj, Kiran Kiran, Lokesh lingappa
Keywords
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