Topical Curcumin: A Review of Mechanisms and uses in Dermatology
Journal Title: International Journal of Dermatology and Clinical Research - Year 2017, Vol 3, Issue 1
Abstract
Curcumin, the active ingredient in the spice turmeric, has been used in many Eastern countries for its known anti-inflammatory activity. Recently, analysis of multiple studies have cast doubt with regard to the efficacy of oral curcumin in several diseases. While the effectiveness of oral curcumin is hindered by its low bioavailability and poor absorption by the oral route, this is not the case for topical curcumin. In this review, we discuss the mechanisms for its anti-inflammatory and anti-apoptotic activity based on its inhibitory activity on the enzyme, phosphorylase kinase, and present evidence for its salutary effects on burns, wounds, surgical scars, photo-damaged skin and psoriasis.
Authors and Affiliations
Heng Madalene CY
Keywords
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- EP ID EP341576
- DOI 10.17352/2455-8605.000020
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