TOPICAL PROPRANOLOL THERAPY FOR INFANTILE HEMANGIOMA: A RETROSPECTIVE MULTI-INSTITUTION STUDY IN THE EASTERN REGION OF LIBYA.
Journal Title: International Journal of Advanced Research (IJAR) - Year 2019, Vol 7, Issue 6
Abstract
There has been a paradigm shift from steroids to propranolol for the pharmacologic treatment of infantile hemangiomas (IHs); however, the outcomes for such treatment were not well studied. In addition, there is no previous published data about the treatment of IHs in Libya. The purpose of this study is to compare the efficacy of topical propranolol versus intralesional steroid therapy for IH children in Libya. A retrospective review was conducted on patients with IH treated with either topical propranolol or intralesional triamcinolone with dexamethasone therapy, during the period 2014 - 2018. Hemangioma characteristics including the time to heal and percentage of lesion size reduction, were compared as per before and after each type of treatment. Most of the IH cases were females with an age range of 1-6 months. Mean percent reductions in lesion size following both topical propranolol and intralesional triamcinolone with dexamethasone therapy were 53% and 50% respectively. Taking into consideration the prominent side effects of using steroids, then, propranolol could replace systemic corticosteroids as first-line therapy for IH.
Authors and Affiliations
Salma A. Bukhatwa , Zainab Albrgathi , Zainab Salem , Hanady Faraj and Mariam Ehwiw.
Keywords
Related Articles
- EP ID EP611387
- DOI 10.21474/IJAR01/9216
- Views 67
- Downloads 0
EFFECT OF PSYCHO EDUCATIONAL PROGRAM ABOUT CONTROL OF SUICIDAL IDEATION AMONG PSYCHOTIC PATIENTS ON NURSING STAFFS KNOWLEDGE AND PRACTICE.
Suicide is a tragic event with strong emotional repercussions for its survivors and for families of its victims. Suicide is considered a serious public health problem around the world, it is the major cause of death and...
MINIMALLY INVASIVE TECHNIQUES FOR REGENERATIVE THERAPY.
Periodontal regeneration remains the corner stone of periodontal therapy. Newer techniques have emerged to overcome the pitfalls in conventional surgical techniques. Minimally invasive surgery (MIS) is a method of surgic...
PERICARDIOCENTESIS VS SUBXYPHOID PERICARDIOTOMY - COMPARISON OF EFFICACY AND SAFETY
Background:-Comparison of safety and effectiveness of pericardiocentesis versus subxyphoid pericardiotomy in patients with large pericardial effusion (PE) defined as more than 2 cm fluids behind the posterior wall of lef...
AN ECONOMIC STUDY ON TOWN PANCHAYAT IN TAMIL NADU.
Tamil Nadu is the first State to have introduced a classification in the status of local bodies as ?Town Panchayat?, which was planned as a transitional body between Rural and Urban Local Bodies. Among the Local Bodies,...
EFFECT OF REPLACEMENT OF FISHMEAL WITH SOME CHEAP ANIMAL PROTEIN SOURCES ON THE GROWTH PERFORMANCE OF JUVENILES OF LABEO ROHITA.
During the present investigation, various animal proteins were tested for their ability to replace the expensive fishmeal with some cheap and alternate protein sources. Three experimental diets i.e A1, A2 and A3 were for...