Total antioxidant and oxidant status in obese children without insulin resistance
Journal Title: Dicle Tıp Dergisi - Year 2014, Vol 41, Issue 2
Abstract
Objective: Oxidative stress in obese children may lead in adulthood serious conditions such as coronary heart diseases or type 2 diabetes mellitus. In childhood oxidative stress is associated with insulin resistance or extreme obesity. In this study, we aimed to evaluate oxidative stress status in moderately obese children without insulin resistance. Methods: A total of 38 obese children (21 male, 17 female) without insulin resistance, mean aged 9.4±3.8 years) and 51 normal weight children (25 male, 26 female) as the control group, mean aged 9.3±3.9 years) were enrolled to the study. Total oxidative status (TOS), total antioxidant capacity (TAC) were measured and oxidative stress index (OSI) was calculated. Results: The results reveal that obese children had lower TAC than normal weight children (2,27±0,28 vs. 2.76±0.35 mmol Trolox Eq./L; p<0,001). There was no statistical difference between obese and control groups regarding TOS (6,08±3,63 vs 5.25±4.16 μmol H2O2 Eq./L; p=0.333). OSI was higher in obese group (2.65±1.52 vs 1.92±1.56; p=0.029) Conclusion: Balance between oxidant and antioxidant system is disrupted due to the reduced TAC even in moderately obese children without insulin resistance. Further studies should also be performed to evaluate the beneficial effects of dietary intake of antioxidants in these children. Key words: children, obesity, oxidative stress
Authors and Affiliations
Ayşegül Demir, Ufuk Erenberk, İlker Özgen, Emin Özkaya, Aysel Türkmen, M. Ruşen Dündaröz , Özcan Erel
Keywords
Related Articles
- EP ID EP147421
- DOI 10.5798/diclemedj.0921.2014.02.0412
- Views 59
- Downloads 0
Sol ventriküler mikrofistülizasyon: koroner arterleri normal olan bir hastada iskeminin nadir bir nedeni
Fizik egzersiz esnasında göğüs ağrısı oluşan 71 yaşında bayan hasta kardiyoloji bölümüne başvurdu. Miyokard perfüzyon sintigrafisinde inferior ve anteroapikal segmentlerde hipoperüzyon saptandı. Selektif koroner anjiy...
Videoflorografide saptanan bir özofagorespiratuar fistül olgusu
Bu olgu bildirisinde, yemek sırasında tekrarlayan öksürme ve boğulma nöbetleri olan 59 yaşında bir kadın hasta sunulmuştur. Geçmişinde, mediastinal lenf bezlerinde metastatik tümör bulunması nedeniyle radyasyon ve kem...
Prevalence of burning mouth syndrome in adult Turkish population
Burning mouth syndrome (BMS) is defined as a chronic orofacial pain condition, characterized symptomatically by burning pain localized to the tongue and lips or may involve the entire oral cavity. The prevalence of burni...
Our results of large area mitomycin C application rabeculectomy in cases with advanced glaucoma
Objective: To evaluate large area Mitomycin-C (MMC) applied trabeculectomy results in advanced glaucoma patients in which targeted intraocular pressure (IOP) can not be achieved with maximum medical therapy. Methods:...
The identification of Candida species isolated from clinical specimens of immunocompromised patients with PCR and determination of antifungal resistance genes with RFLP and sequencing analysis
Objectives: The aim of this study is to investigate PCR technique and antifungal resistance genes with RFLP and sequencing analysis in Candida species isolated from clinical specimens of immune-compromised patients....