Toxicity of Sponge Extract Xestospongia testudinaria
Journal Title: International Journal of Engineering and Science Invention - Year 2018, Vol 7, Issue 5
Abstract
Sponge is a highly prospective bioactive material from the ocean. This study aims to determine the toxicity of Xestospongia testudinaria sponge extracts collected from Sanur beach, Bali, Indonesia. Sponges are one biota that contains bioactive compounds from the sea that are very prospective. Nearly 5,000 compounds have been successfully isolated from these animals with various activities such as antimicrobials, antifungal, antiviral, and anticancer. The preliminary test for potentially anticancer material was to determine the toxicity of the material. The method used to determine the toxicity was the Bhrine Shrimp Lethality Test (BSLT) method. Based on the results of this study showed that X. testudinaria sponge methanol extract was toxic to Artemia salina larva with LC50 of 31.62 ppm, while that of n-hexane extract showed less toxic because of its LC50 value of 177.83 ppm.Based on the results of this study, it can be concluded that the methanol extract of X. testudinaria sponge collected from Sanur beach, Bali, Indonesia was toxic against A. salina larvae with LC50 of 31.62 ppm.
Authors and Affiliations
I M. D. Swantara, W. S. Rita
Keywords
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