Toxicological Study of Rasamanikya by L.D. 50 Method
Journal Title: International Journal of Ayurveda and Pharmaceutical Chemistry - Year 2017, Vol 0, Issue 0
Abstract
Rasamanikya is a single drug formulation of Hartal (Arsenic Trisulphide).Hartal is a drug categorised as one of the two dhatuvisha described by AcharyaSushruta. Rasmanikya is a drug which is useful in several diseases. It precipitates the need of toxicity study of Rasamanikya. In present study, Rasamanikya has been prepared as per the classical text and then its analytical as well as toxicity studies have been carried out. The SEM (Scanning Electron Microscope) with EDAX (Energy Dispersive X-Ray Analysis) analytical study shows 56.80% of Arsenic and 43.20% of Sulphur in the Rasmanikya. The toxicity study did not show any toxicity signs or mortality in Albino mice when given in normal dose.
Authors and Affiliations
Bhange Pankaj, Undale Vidya, Bhatambre Yogesh
Keywords
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