Transition of Oral Leukoplakia Into Oral Verrucous Carcinoma – A Case Report with Literature Update
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 1
Abstract
Introduction: Verrucous carcinoma (VC) is an exophytic lesion,which classically can be seen in the oral cavity, larynx, genitalia, skin, and esophagus. It has a slow growth potential and is an alternative form of oral squamous cell carcinoma. It is recognized by its local aggressiveness with minimal metastatic activity. It is also called as “snuff dipper’s cancer” as its association with tobacco chewers and snuff users. According to a recent literature, VC has a strong relation with human papilloma virus which has a potential role in its growth and development. Though clinical presentation is classic for VC, histopathological diagnosis needs expertise opinion. It is said that often VC is preceeded by long standing potentially malignant disorders (PMD) in the oral cavity. Case report: Here we report a case of verrucous carcinoma with a pre existing history of oral leukoplakia since long duration.The casewas managed surgically and the patient is on follow up without any complication since a year. Conclusion: From the case presented here we could say that potentially malignant disorders (PMD) of oral cavity should be correctly diagnosed and immediately the treatment should start to prevent further complications. Long term follow up of patients with PMD is must. The Prognosis of VC is often good after surgical treatment.
Authors and Affiliations
Usama A. Kharadi, R. S. Birangane, Sanjeev Onkar, Noopur Kulkarni
Keywords
Related Articles
- EP ID EP424891
- DOI -
- Views 103
- Downloads 0
The Role of Ormeloxifene in the Management of Dysfunctional Uterine Bleeding: A Prospective Clinical Study
Introduction: The term dysfunctional uterine bleeding (DUB) is used for abnormal uterine bleeding occurring in the absence of identifiable pathology. A number of drugs are available for management of DUB – nonsteroidal a...
Screening of Nucleostemin p53-Independent Signal Pathway in NB4 Leukemia Cell
Introduction: Nucleostemin is a newly discovered nucleoprotein which is found to be highly expressed in the undifferentiated cells like stem cells and cancer cells. It is an important G1/S checkpoint regulator. The aim o...
Association of Alpha-1-Antitrypsin with Asthma
Introduction: Asthma is a chronic inflammatory disease of the airways that affects people of all ages. Alpha-1-antitrypsin (or alpha-1-proteinase inhibitor) is the most abundant circulating proteinase inhibitor. Alpha-1-...
Study of Clinical Profile and Management of Incisional Hernia
Introduction: Incisional hernia is a serious postoperative complication of surgical intervention. Incisional hernia is diffuse extrusion of peritoneum and abdominal contents through the weak scar of an operation of abdom...
A Role of N-Cadherin in Tumor Progression and Prognosis of Epitheliual Malignancy
Epithelial cells typically express E-cadherin, mesenchymal cells express various cadherins, including N-cadherin, R-cadherin and cadherin-11. N-cadherin is also known as neural-cadherin, non-epthelial cadherin or cadheri...