Abstract

Various techniques have been attempted in the past to truly regenerate the lost bone structures. Owing to its stimulatory effect on angiogenesis and epithelialization, concentrated growth factor (CGF) is an excellent material for enhancing bone healing. The purpose of these case series is to document the beneficial role of CGF in the healing of different bone defect areas. This report describes four female patients presented with (lateral cyst on tooth 22; periimplantitis on mandibular left first premolar area; furcation lesion on tooth 36, periapical abcess on teeth 11-21). Mucoperiosteal full-thickness flaps were elevated to perform the surgical debridement of lesion areas in all patients. Then, minced CGF mixed with bone graft was applied to fill the defects. Recall radiographs of cases showed satisfactory healing of the bony defects. According to the results obtained in these case reports, the positive clinical impact of additional application of CGF with bone graft materials in treatment of bone defects is based on significant radiographic defect bone fill.

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