Treatment of Intrahepatic Cholangiocellular Carcinoma with Y-90 Labelled Microspheres
Journal Title: Nükleer Tıp Seminerleri - Year 2019, Vol 5, Issue 2
Abstract
Intrahepatic cholangiocellular carcinoma (ICC) is a rapidly progressive malignancy of intrahepatic bile duct epithelium. ICC is the second most common primary malignant tumor of the liver which accounts for 10% to 20% of primary liver tumors. At the present time, surgery has been accepted as the only potential curative treatment method, however, only 30% of patients are eligible for surgical treatment because of anatomical situations, insufficient liver reserve, or concomitant comorbidities. For ICC patients who are ineligible for surgical treatments, therapies like systemic chemotherapy, thermal or nonthermal ablations, and external radiotherapy are applied as an initial treatment. In addition, less side effects advantage over systemic chemotherapy, yttrium-90 marked microsphere treatment has been prominent especially in the last years. The majority of the recent studies have proved the effectivity of yttrium-90 labelled microsphere treatment in ICC and accepted this treatment as a safe treatment. However, the variability of the patients’ demographical features in these studies leads to different outcomes which is thought to be as a result of individual and biological discrepancies.
Authors and Affiliations
Hüseyin Tuğsan Ballı
Keywords
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- EP ID EP604007
- DOI 10.4274/nts.galenos.2019.0021
- Views 133
- Downloads 0
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