TREATMENT OUTCOME AND DETERMINANTS AMONG PATIENTS WITH VISCERAL LEISHMANIASIS IN ARBA MINCH GENERAL HOSPITAL LEISHMANIASIS RESEARCH AND TREATMENT CENTER, GAMO GOFA ZONE, SNNPR, ETHIOPIA
Journal Title: INNOVATIVE JOURNAL OF MEDICAL AND HEALTH SCIENCE - Year 2018, Vol 8, Issue 8
Abstract
- Introduction: Visceral Leishmania represents a challenging diagnosis and treatment because the clinical picture of Visceral Leishmaniasis, so that the treatment outcome is compromised with many factors, thus study try to asses real picture of treatment outcome with determinants. Objective: To assess treatment outcome and determinant factors among patient with visceral Leishmaniasis in Arba Minch General Hospital Leishmania Research and Treatment Center. Methods: Institution-based, Cross-sectional, retrospective study was conducted among Leishmaniasis patients in Arba Minch general hospital. Patient charts that have been treated from January 2011-December 2015 were reviewed. A total of 348 charts were selected by Simple Random Sampling technique and included in the study. The data were entered and cleaned using Epi-info version 7.0 and analysis was carried out using SPSS-20 statistical packages. Multi-variate logistic regression analysis was carried out to identify the independent predictors of treatment outcome. Result: A total of 348 patient's charts were included in the study. The prevalence of poor outcome was found to be 8.6%. The presence of bleeding/Epsitaxis[AOR=5;95% CI:1.3,19.3], tuberculosis[AOR=3.7;95%CI:1.83,6.3], septic syndrome[AOR=4.3;95% CI: 6.1,32], and adverse drug side effect[AOR=4.5;95%CI:2.73,13.6] were the independent predictors of treatment outcome. Conclusion and recommendation: The prevalence of poor treatment outcome among patients with VL in the study area is high. Concomitant infection; bleeding/Epsitaxis, tuberculosis, septic syndrome and adverse side effect were independently associated with poor treatment outcome. The clinical management of VL in co-infected patients is a major challenge that requires new treatment approaches to improve its outcome.
Authors and Affiliations
AMSALU Mr. ALEMU TAMISO*
Keywords
Related Articles
- EP ID EP443446
- DOI 10.15520/ijmhs.v8i8.2279
- Views 69
- Downloads 0
Molecular description of alpha-hemolysin producing Escherichia coli isolates from extraintestinal source
Context:Alpha-hemolysin (Hly) is a common exotoxin produced by Escherichia coli, which plays an important role as a virulence factor in a number of clinical infections. There exist other virulence propertie...
A Renal congenital Anomaly - unilateral extracalyceal Ectopic Right Kidney With Multiple Aberrant Renal Vessels
 Routine dissection of the abdomen of a 63 year old male cadaver in the Dept. of Anatomy Hi- tech medical college Rourkela., revealed the presence of a rudimentary ectopic right kidney fused to the lower pole of the lef...
Why Tall Individuals are More Prone to Cancer
Cancer has many definitions. Human has capacity to store cancer in long time and early cancer is healthy that can kept under control. The hidden survival cancer cell in body missed by modern physicians that keep millions...
Thyroid dysfunction in elderly: Experience of a tertiary care centre in Kerala
Background: There is limited data regarding the prevalence of thyroid disorders in elderly from India. Methods: All subjects aged ≥ 60 years, who underwent estimation of thy-roid function tests (TFTs) on their f...
Hygiene and Endoecology, Light Bioenergy and Natural Ecology, Balanced Mentality and Spiritual Life as Criterion of Health
Despite many attempts to measure health, it wasn’t offered any scale which wouldhave practical value in this plan. Absence of the uniform point of view on a problemof essence of health is obvious. A specification of esse...