TREATMENT OUTCOME AND EFFICACY OF ANTI-TUBERCULOSIS TREATMENT IN TUBERCULOSIS PATIENTS PUT ON DOTS IN RNTCP IN CENTRAL INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 15
Abstract
BACKGROUND Tuberculosis (TB) remains a global public health problem and a major cause of death from a single infectious agent among adults in India and other developing countries. Aims & Objectives- The aim of this study is to characterise outcome and efficacy of tuberculosis treatment among patients put on DOTS in RNTCP. MATERIALS AND METHODS This is a retrospective study of diagnosed TB patients of all age groups attending OPD of various departments of LN Medical College and JK Hospital, Bhopal, MP (India), between the period of January 2012 and October 2015. RESULTS Total 454 patients were found eligible for this study who were diagnosed and received full course of ATT under DOTS in RNTCP. In different age groups percentages of patients observed were 12.11%, 31.27%, 22.68%, 13.65% and 20.26% in 0 - 14 years, 15 - 25 years, 26 - 35 years, 36 - 45 years and above 45 years respectively. CONCLUSION Maximum patients, 31.27% (142/454) were registered in the age group of 15 - 25 years. Overall, treatment outcome were observed as follows- 82.81% treated successfully, 7.70% defaulted, 4.18% failed and 3.96% died. Higher percentage of treatment was successful (98.18%) and was observed in the age group of 0 - 14 years, whereas higher percentage of both defaulter (14.13%) and mortality (13.04%) with lower treatment success rate (65.21%) was observed in the age group of above 45 years. Higher percentage of defaulter, failure and mortality were observed in males and category I in comparison to females and category II.
Authors and Affiliations
Ratan Kumar, Rajesh Kumar Ahirwar, Lokendra Dave, Nishant Srivastava, Adarsh Bajpai, Sapna Jain, Aditya Gargava, Shyam Krishna Vaish
ANTI-CONVULSANT ACTIVITY OF GANAXOLONE ALONE AND IN COMPARISON WITH STANDARD ANTI-EPILEPTIC DRUGS IN RODENT MODELS
[b]BACKGROUND[/b]: Presently, treatment of epilepsy with standard anti-epileptic drugs is associated with a number of shortcomings inviting us to study newer agents that would overcome th...
STUDY ON CARDIAC INVOLVEMENT IN SYSTEMIC SCLEROSIS
BACKGROUND Systemic sclerosis is a generalised disorder of connective tissue characterised by diffuse vascular lesions, fibrosis of skin and major organ systems involvement including cardiac, pulmonary and gastrointestin...
ANALYSIS OF PLATELET INDICES AND ITS PREDICTIVE VALUE IN DIAGNOSIS OF THROMBOCYTOPENIA
BACKGROUND Thrombocytopenia can be due to decreased production of platelets in bone marrow or due to increased destruction. Aetiology of thrombocytopenia can be evaluated by determination of platelet indices, whether it...
A RARE CASE OF DEBILITATING HEADACHE AND ANAPLASTIC OLIGOASTROCYTOMA OF FRONTAL LOBE
PRESENTATION OF CASE A 25-year-old female patient from Mandya, Karnataka came to Ophthalmology OPD at Vasan Eye Care, Bangalore. Complaint of headache since one month. Headache initially was bi-frontal then gradually bec...
A STUDY OF ASSOCIATION BETWEEN BIRTH SEASONALITY, BIRTH ORDER AND SPACING IN SCHIZOPHRENIC PATIENTS
BACKGROUND Schizophrenia is a major psychiatric illness characterised mainly by abnormal thinking as well as changes in mood and perception. Western studies tell that Schizophrenics are born in monsoon contrary to Indian...