Trend in Seroprevalence of Hepatitis B Virus Infection Among Blood Donors In A Tertiary Care Teaching Hospital In Tirupati
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 5
Abstract
Introduction: Hepatitis B virus (HBV) is a member of hepadna virus family – a DNA virus which is transmitted percutaneously (intravenous drug abuse / blood transfusion), perinatally and sexually. Transfusion associated Hepatitis B virus (TAHBV) is one of the major transfusion transmitted infections (TTI) in India and has high incidence in patients receiving multiple blood transfusions. Material and Method: This study was carried out in a tertiary care teaching hospital. Retrospective analysis of donor profiles for a period of six years was analysed to assess the distribution of seropositive cases in relation to age, sex, and trend. The analysis was performed by enzyme linked immunosorbent assay (ELISA). Results: A total of 43839 blood units were screened amongst which 775 (1.76%) were positive for Hepatitis-B. There were 754 (1.71%) males and 21 (0.04%) females. Replacement donors showed more seropositivity compared to voluntary donors. Seropositivity was common in young donors. Conclusion: In the present study, there is gradual decline in prevalence of HBV from 2012 to 2017 which can be attributed to effective pre donation counseling of donors, encouragement of voluntary donation and increasing awareness in society etc. Advanced techniques of screening, immunization, health education to high risk groups ensures better blood transfusion services.
Authors and Affiliations
B. V. Sai Prasad, Md Khader Faheem, B. Anuradha, A. Venkata Lakshmi, C. Sushma, G. Lavanya
Keywords
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- EP ID EP374278
- DOI 10.9790/0853-1705032933.
- Views 47
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