Triple negative breast cancer – Our experience
Journal Title: MedPulse -International Medical Journal - Year 2016, Vol 3, Issue 8
Abstract
Triple negative Breast cancer constitutes 10-25% of patients with Breast cancer. TNBC is an aggressive phenotype and has poor prognosis. We restrospectively analysed 30 triple negative Breast cancer patients attending our out patients department among 200 Breast cancer Patients. The incidence of TNBC was 15% and most of them were post menopausal 73.33% (22/30) with mean age was 54.96 (Range 98-74 years) Most of them had Invasive ductal cancer 100% (30/30) and were high grade 3 (86.66%) (26/30). 2 patients (6.66%) presented with metastatic disease. one patient with lung metastasis and one patient with locally advanced disease with fungating mass over Breast and liver metastasis. 15 patients (50%)developed Recurrence and Distant metastasis on follow up. 2 patients had chest wall Recurrence, 1 had chest wall recurrence with lung metastasis,4 had Bone metastasis, 1 had lung metastasis, 1 had lung metastasis with contralateral breast cancer, 1 had liver mestastasis with contralateral Breast Cancer, 1 had lung with Bone and Brain metastasis, 1 had lung with liver, Brain and adrenal metastasis, and 1 had chest wall recurrence with supraclavicular lymph node reccurence with Bone metastasis, 1 had chest wall recurrence with supraclavicular lymph node recurrence with lung and Bone metastasis, 1 had supraclavicular lymph node recurrence. The mean disease free survival was 19.8 months (range 3-52 months) and overall survival was 27.3 months (range 9-98 months). 4 patients (13.33%) died during follow up. Hence Triple Negative Breast cancer is aggressive with rapid progression leading to mortality in younger patients.
Authors and Affiliations
Veenu Agrawal, Tejal Vadhan, S Shewalkar, A Gaikwad
Keywords
Related Articles
- EP ID EP207502
- DOI -
- Views 116
- Downloads 0
Effect of APH on mode of delivery
Introduction: Antepartum hemorrhage (APH) is a grave obstetrical emergency and is a leading cause of maternal and perinatal mortality and morbidity. Various authors recommend various mode of delivery in APH. Aims and Obj...
Isolated patent ductus arteriosus with right sided aortic arch: percutaneous closure with amplatzer device
Introduction: The association of a right aortic arch with an isolated patent ductus arteriosus is rare, especially when there are no other intracardiac anomalies. We report a case of successful transcatheter closure of P...
Role of 24-hour ambulatory blood pressure recording over office BP recording in clinical practice
Aims and Objectives: To study Role of 24-hour ambulatory blood pressure recording over office BP recording in clinical practice. Material and Methods: An observational, analytical and population based study was conducted...
Analytical study of drainage of breast abscess by open drainage with primary suturing with negative suction drain and conventional incision and drainage
Aim And Objectives: To compare and study efficacy of open drainage with primary suturing with negative suction drain over conventional incision and drainage in regards to Post operative pain, Duration of hospital stay, S...
Study of complications following lichtenstein mesh repair and Bassini’s repair for primary inguinal hernia
Introduction: For hernia, many surgical procedures have been described. Because of the recurrence of hernia, there is no standard treatment for hernia till now. In review of literature, there were recurrences even with t...