Tumor Conditioning Regimens: An Evolution in Cancer Treatment that Relies on Short-Term Sacrifice for Long-Term Gain
Journal Title: Gynecology and Obstetrics Research – Open Journal - Year 2017, Vol 4, Issue 2
Abstract
In this commentary, the authors discuss a new concept for tumor treatment, which is based on observations from published studies and clinical practice protocols. This new treatment regimen, which we coin “Tumor Conditioning Regimens,” abbreviated as TCRs is based on the idea that by conditioning tumors with oxygenation, increasing mutation loads or normalizing vessels, we create a permissive environment for tumor growth in the short-term, which will eventually in the long run benefit tumor regression. In our view, such a strategy of making things worse before they get better for tumor treatment has not been articulated in the literature although anecdotal examples exist, which we have highlighted in the commentary. This commentary serves as a discussion starter for the scientific and clinical community as to the pros and cons of such an approach.
Authors and Affiliations
Erin Bishop, Ramani Ramchandran
Keywords
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- EP ID EP553846
- DOI 10.17140/GOROJ-4-143
- Views 162
- Downloads 0
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