Tumor Genesis Syndrome in a Paediatric Patient with Burkitt Lymphoma of Abdomen
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 8
Abstract
Electrolyte disturbances are common in patients with hematological malignancies and are mostly due to tumour lysis syndrome. Tumour genesis syndrome although uncommon occurs when rapid cell proliferation and DNA synthesis deplete extracellular phosphate. These ominous electrolytes disturbances may indicate rapid tumour genesis and require urgent treatment intervention to halt the crises of rapid leukemic cell proliferation. A 4 -year-old boy diagnosed with Burkitts lymphoma of abdomen developed severe hypophosphatemia prior to treatment initiation followed by acute renal failure requiring hemodialysis on treatment initiation. With appropriate timely supportive care child recovered and eventually completed the planned chemotherapy schedule and is under follow up now.
Authors and Affiliations
Prasanth VR, Guruprasad CS, Priyakumari T
Keywords
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