TUMOR NECROSIS FACTOR ALPHA (TNF-α) AND ESTROGEN HORMONE IN OSTEOARTHRITIC FEMALE PATIENTS

Journal Title: Indian Journal of Clinical Biochemistry - Year 2006, Vol 21, Issue 1

Abstract

Osteoarthritis of knee joints is a disease of old age in both sex. It is very common after the age of 40 years in elderly females or in postmenopausal phase of females. It is characterized by narrowing of space in joints due to inflammation. The exact mechanism of inflammation in this disease is not yet clear. Tumor necrosis factor alpha (TNF-α) may involve in onset of disease. The present study is being carried out in 130 female subject of age group 40-60 years suffering from osteoarthritis of knee joints and 50 normal healthy control female subjects. A correlation is made between TNF-α and estrogen and found significant inverse correlation (r

Authors and Affiliations

Pradeep Sharma*, Neelima Singh*, Vinod Singh**, Sanjeev Singh*, Harsh vardhan Singh*and Sameer Gupta***.

Keywords

Related Articles

SERUM LIPIDS IN HYPOTHYROIDISM : OUR EXPERIENCE

In order to determine whether the screening of lipid profile is justified in patients with hypothyroidism we estimated serum lipids in cases having different levels of serum TSH. 60 patients of hypothyroidism in the age...

MATERNAL AND FETAL INDICATORS OF OXIDATIVE STRESS DURING INTRAUTERINE GROWTH RETARDATION (IUGR)

The present study demonstrates the possibility of increased lipid peroxidation and protein oxidation in both maternal and fetal erythrocytes as markers of oxygen radical activity during intrauterine growth retardation....

PREVENTION OF ISOPROTERENOL-INDUCED CARDIAC HYPERTROPHY BY EUGENOL, AN ANTIOXIDANT

Recent reports on the involvement of calcineurin in cardiac hypertrophy and its susceptibility to free radicals, prompted us to examine possible beneficial effects of dietary antioxidants in this regard. In continuation...

A STUDY OF THE INTERACTION BETWEEN ROPRANOLOL AND NSAIDs IN PROTEIN BINDING BY GEL FILTRATION METHOD

Drug protein binding phenomena can lead to some interesting drug - drug interactions when one drug displaces another in the binding site. Studies of protein binding are conducted by several methods including equilibriu...

Download PDF file
  • EP ID EP91213
  • DOI -
  • Views 127
  • Downloads 0

How To Cite

Pradeep Sharma*, Neelima Singh*, Vinod Singh**, Sanjeev Singh*, Harsh vardhan Singh*and Sameer Gupta***. (2006). TUMOR NECROSIS FACTOR ALPHA (TNF-α) AND ESTROGEN HORMONE IN OSTEOARTHRITIC FEMALE PATIENTS. Indian Journal of Clinical Biochemistry, 21(1), 205-207. https://europub.co.uk/articles/-A-91213