Two cases of disseminated superficial actinic porokeratosis (DSAP) and treatment literature review
Journal Title: Nasza Dermatologia Online - Year 2018, Vol 9, Issue 3
Abstract
Background: Disseminated superficial actinic porokeratosis (DSAP) is characterized by asymptomatic multiple papules with annular keratotic rim distributed symmetrically on the sun-exposed areas. Many approaches have been proposed in the past for treating DSAP, but the therapy is still a challenge for every physician, mostly because of the frequent relapses of the disease and the multiplicity of the skin lesions. Material and Methods: Two case reports were reported emphasizing the challenges of treatment approach. Therefore, a systemic English literature review was conducted searching Medline database using PubMed Central and Ovid software as search interface to collect evidence based on the various treatment modalities for DSAP. Results: The initial search yielded 146 articles, but only the relevant case reports, case series and studies relating to the treatment of DSAP have been described and summarized in a table. For each different therapy the efficacy of each treatment, side effects, cost-effectiveness and authors’ recommendations were reported. Conclusion: Several factors need to be considered prior to physicians’ decision of the most appropriate treatment for each patient like age, the extent of body surface area involvement, patients’ medical history and social situation, the available resources, the side effects and cost- effectiveness of each treatment. However, l the exact value of each treatment is difficult to determine owing to the lack of controlled studies evaluating their efficacy. Due to few incidences of squamous cell carcinoma, patients need to be followed up and monitored closely for any early detection of recurrence or possible onset of malignancies.
Authors and Affiliations
Elena Thomaidou
Keywords
Related Articles
- EP ID EP358816
- DOI 10.7241/ourd.20183.3
- Views 74
- Downloads 0
IgD, cyclooxygenase-2 and ribosomal protein S6-PS240 immune response in a case of early psoriasis
Psoriasis is an inflammatory skin disease. Five classic types of psoriasis have been defined: plaque, inverse, pustular, guttate, and erythrodermic. The early psoriasis immunologic skin immune response is not well unders...
Pattern of patch test reactivity among patients with clinical diagnosis of contact dermatitis: A hospital-based study
Introduction: The patterns of positive patch test in Nepal have not been defined so far. The aim of this study was to describe the patterns of patch test reactivity in suspected Allergic Contact Dermatitis (ACD) patients...
Renbök phenomenon: Alopecia areata sparing psoriasis plaques
-
Lupus erythematosus, thyroiditis, alopecia areata and vitiligo – A multiple autoimmune syndrome type 3 case presentation
The combination of at least three autoimmune diseases in the same patient has defined as multiple autoimmune syndrome (MAS). Abnormalities of T cell-mediated immunity and humoral immunity have been described previously i...
Spectrum of viral skin infections in patients attending the dermatology clinic at King Fahd Hospital of the University in Alkhobar, Kingdom of Saudi Arabia during the period 2010 – 2014
Introduction: Viral skin infections are an important disease group in the dermatology field. Many factors play a role in the incidence of skin diseases. There are only a few reports of surveys conducted on the prevalence...