Two pediatric Henoch-Schönlein purpura cases whose severe gastrointestinal hemorrhage treated by cyclophosphamide
Journal Title: Dicle Tıp Dergisi - Year 2013, Vol 40, Issue 2
Abstract
Henoch-Schönlein purpura (HSP) is a vasculitis, that involves various organ systems and show different clinical picture. It can be presented with purpura-like skin rash, abdominal pain, arthritis and renal involvement. Rarely, severe skin, gastrointestinal (GIS) and renal involvement occur and can lead to early or late complications. In this paper, it was aimed to report, two HSP children with severe GIS involvement as recurrent intestinal hemorrhage, which did not respond to high dose intravenous steroids, but successfully treated by intravenous cyclophosphamide. One of our patients had also severe necrotic skin lesions that necessitate skin grafting and the other had severe renal involvement as nephrotic syndrome. Intravenous cyclophosphamide may be useful in children with HSP, when severe GIS involvement not respond to high dose steroids. Key words: Henoch-Schönlein purpura, severe system involvement, cyclophosphamide, management
Authors and Affiliations
Aydın Ece, Sevgi Yavuz, İlhan Tan, Ünal Uluca, Duran Karabel
Premenopozal ve postmenopozal kadınlarda lipit profili ve plazma aterojenik indeksinin karşılaştırılması
Amaç: Menopoz ile birlikte hormonal durum, metabolizma ve lipit profilinde bir takım değişiklikler meydana gelir. Çalışmamızın amacı yaşın ve menopozun lipit profilinde meydana getirdiği değişiklikleri incelemektir. Yön...
Comparison of patient-controlled analgesia and continuous infusion with intravenous tramadol in post-thoracotomy analgesia
Objectives: We aimed to compare the consumption, and analgesic and adverse effects of tramadol that given via continuous intravenous infusion and intravenous patient-controlled analgesia. Materials and methods: Forty pa...
Coexistence of hyperthyroidism and thyroid cancer
Objective: Thyroid cancer can be associated with thyrotoxicosis caused by Graves' disease, toxic multinodular goiter, or toxic nodular goiter. The aim of this study was considered to be endemic in our region have receiv...
Frequency of childhood abuse in university students
Objectives: Child abuse or bad behaviors against children is a social, medical problem and is old as the history of humanity. The analysis of the frequency of childhood abuse in university students and the comparison...
Clinical Outcomes of Penile Prosthesis Implantation Surgery
Objective: We aimed to evaluating the outcomes of inflatable penile prosthesis implantations and partner satisfaction. Methods: Data of 52 patients who underwent penile prosthesis implantation in single center betwee...