Ultra-sensitive electrochemical on-line determination of Clarithromycin based on Poly(L-Aspartic Acid)/Graphite Oxide/Pristine Graphene/Glassy Carbon Electrode
Journal Title: Asian Journal of Nanoscience and Materials - Year 2018, Vol 1, Issue 2
Abstract
In this work, a novel and extra sensitive method for on-line continues monitoring of Clarithromycin in whole blood sample was introduced based on coupling of electro-membrane extraction (EME) and stripping fast Fourier transform continuous cyclic voltammetry (SFFTCCV). In this method, the potential waveform was continuously applied on a Poly(L-Aspartic Acid)/Graphite Oxide/Pristine Graphene/Glassy Carbon Electrode and the electrode response was obtained by detracting the background current and in the following integrating the current in the specific potential range of oxidation of the analyte. This method was performed by applying a DC potential and migration of Clarithromycin from the sample solution into a layer of 4-methyl-2-pentanol that is immobilized in the pores of the sheet membrane and then migration into the acceptor solution. A low and valuable detection limit of 1.0 ng ml-1 and quantification limit of 6.0 ng ml-1 are considered as a part of the sensible results of this experiment. Furthermore, an efficient linearity in the range of 6.0-1000 ng ml-1 were found.
Authors and Affiliations
Navid Rabiee, Moein Safarkhani, Mohammad Rabiee
Keywords
Related Articles
- EP ID EP286024
- DOI -
- Views 93
- Downloads 0
Theoretical insights of the electronic structures, conductivity, and aromaticiy of Graphyne and Si-doped Graphynes
In the present research, the dipole moment, electronic structure, frontier orbitals energy, and aromaticity in the graphyne and Si-doped graphynes were studied with M062X quantum chemical computation. The relative energi...
Synthesis of γ-Fe2O3 Nanoparticles and Catalytic activity of Azide-Alkyne Cycloaddition Reactions
Iron nanoparticles (NPs), due to their interesting properties, low cost preparation and many potential applications in ferrofluids, magneto-optical, catalysis, drug delivery systems, magnetic resonance imaging, and biolo...
Synthesis and characterization of CaO catalyst obtained from achatina achatina and its application in biodiesel production
In this research study, Achatina achatinashells was used as the source of raw material to produce calcium oxide which was used as a catalyst in the production of biodiesel. The main aim of this study was to investigate t...
Nano-Sized and Single Crystal of a 1D Copper(I) Coordination Polymer: Preparation, Characterization, Thermal and Structural Studies
Nano-sized powder of a new 1D copper(I) coordination polymer, [Cu(nba2en)(NCS)]n (1), (nba2en = N,Nʹ-bis(4-ntrobenzylidene)ethane-1,2-diamine, was synthesized using ultrasonic bath assisted and characterized by scanning...
Polyacronitrile Ultra Filtration Membranes Used for Separation of Glycerol from Transesterification Process of Biodiesel production.
In the present study the production of biodiesel was performed by using raw material like soybean oil by trans-esterification process. According to the American Society for Testing and Materials (ASTM), the international...