Ultrasound Ablation in Advanced Pancreatic Cancer Patients – What should be the Next Step?
Journal Title: Pancreas – Open Journal - Year 2016, Vol 1, Issue 1
Abstract
In the last decades the treatment for many diseases has changed dramatically. Open surgery procedures with high morbidity and complication rates, suboptimal clinical results based on large impairment for the patients were replaced by drug treatment or minimally invasive techniques. Examples such as interventional cardiology procedures in acute myocardial infarction, interventional endoscopies in the treatment of hepato-biliary tract diseases, eradication of Helicobacter pylori for gastric ulcer using drugs are good evidence that the words of William Osler “Diseases that harm require therapies that harm less” are valid now-a-days.
Authors and Affiliations
Dobromir Dimitrov
ADAM10 Proteases and Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is the 4th leading cause of cancer-related deaths in the United States and is expected to rise to the second rank by 2020.1 The survival rate of PDAC is estimated at less than 5% a...
Nutritional Support of Patients With the Abdominal Compartment Syndrome During Severe Acute Pancreatitis
There is growing evidence in the literature that development of Abdominal Compartment Syndrome (ACS) in patients with Severe Acute Pancreatitis (SAP) has a strong impact on the course of disease. Incidence of ACS in pati...
Epithelial-To-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Fiction or Fact?
Pancreatic Ductal Adenocarcinoma (PDAC) is one of the most aggressive and lethal tumors, representing the fourth most common cause of cancer death in the Western world, with an estimated incidence of more than 40,000 cas...
β-cell Heterogeneity: The Key to β-cell Replacement Therapy
Cellular heterogeneity is crucial for organisms to adapt to their environmental changes. It provides the morphological, functional and molecular diversity that allows tissues and organs to respond to stressors and mainta...
The Enigma of Type 3c Diabetes in Chronic Pancreatitis
Pancreatogenic or Type 3c diabetes (T3cDM) is relatively a new entry in the complex world of diabetes study. While the general population and physicians are well aware of type 1 and type 2 diabetes mellitus, as evidenced...