Ultrasound/computerized tomography guided fine needle aspiration cytology of liver lesions
Journal Title: IP Journal of Diagnostic Pathology and Oncology - Year 2018, Vol 3, Issue 2
Abstract
AbstractIntroduction Malignancy in the liver primary or metastatic is usually inoperable at the time of diagnosis and as such portends an ominous prognosis A diagnostic modality such as FNAC which offers accuracy with minimal complications and requires minimal intervention at low cost warrants consideration early in the investigation sequenceObjectives The study has been undertaken to evaluate the diagnostic efficacy of ultrasonography USG computerized tomography CT guided FNAC in the diagnosis of liver lesions to correlate FNAC diagnosis with histopathology wherever possible to correlate FNAC diagnosis with radiology diagnosis and to study the cytological patterns of liver lesionsMaterials and Methods A prospective study of 60 patients was conducted between November 2008 and October 2010 After obtaining the detailed clinical and radiological data patients were subjected for FNAC under USG or CT guidanceResults Cytodiagnosis of 60 cases were categorized into 6 10 Nonneoplastic lesions 53 8833 malignant neoplastic lesions and 1 166 as suspicious of carcinoma The different neoplastic lesions were 21 3962 hepatocellular carcinoma 21 3962 metastatic adenocarcinoma 6 1132 metastatic poorly differentiated carcinoma and 5cases 943 of unclassified malignancy Histopathological correlation was available in 11 malignant neoplastic lesions which confirmed the diagnosis Nineteen cases of multiple lesions described by ultrasonography and suggested differential diagnosis of metastasis and HCC proved to be metastatic in 10cases 5263 and HCC in 9 cases 4736 by cytological examination Overall diagnostic accuracy of the FNAC of liver to detect malignant lesions was 9375Conclusion USGCT guided FNAC of liver permits the categorization of more frequent nonneoplastic lesions and neoplastic primary and secondary metastatic malignancy in a simple and rational manner which is helpful for the management of hepatic lesions Ultrasound guided fine needle aspiration of liver has a promising role to play in the diagnosis and classification of liver disease than ultrasonography alone as it requires greater degree of precision to reach diagnostic accuracyKeywords Ultrasound guided Fine needle aspiration cytology Core needle biopsy Hepatic lesions
Authors and Affiliations
Lekha. M. B. , D. C. Prabhu, A. H. Nagarjappa
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