Understanding Iron Metabolism: Lessons from Transfusion-dependent Thalassemia
Journal Title: Oman Medical Journal - Year 2018, Vol 33, Issue 1
Abstract
Iron metabolism is well regulated in humans by a number of proteins, the most important one being hepcidin. Hepcidin inhibits iron absorption at the gastrointestinal (GI) luminal surface through its inhibition of ferroportin. Body iron stores, as well as inflammation, increase the level of hepcidin, thereby leading to decreased GI iron absorption
Authors and Affiliations
Murtadha Al-Khabori, Shahina Daar
Keywords
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- EP ID EP259034
- DOI 10.5001/omj.2018.01
- Views 72
- Downloads 0
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