Unhealed Chin Wound in an Infant with Leukocyte Adhesion Deficiency Type-I
Journal Title: People's Journal of Scientific Research. - Year 2016, Vol 9, Issue 2
Abstract
Leukocyte adhesion deficiency type1(LAD-1) is a rare, autosomal recessive disorder in which phagocyte adhesion, chemotaxis and ingestion of C3 biopsonised microbes are impaired owing to mutations in the gene for CD18 ȕ sub unit of ȕ 2 integrin. We report a 38 day old male infant with LAD-1 and infected unhealed chin wound and history of delayed umbilical cord separation. It is highly recommended that patients who diagnosed with mild to moderate LAD-ȱ with recurrent skin infections and simultaneous weak responses to conventional therapy to undergo bone marrow transplantation (BMT) to prohibit subsequent life-threatening complications
Authors and Affiliations
Ayed A Shati , , Amer A Alshehri , , Halima A Alalkami , , Ali M Alsuheel
Keywords
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