Unified consensus and evolution of the definition of acute-on-chronic liver failure： Seeking common ground while reserving differences
Journal Title: Journal of Clinical Hepatology - Year 2024, Vol 40, Issue 11
Abstract
The concept of acute-on-chronic liver failure （ACLF） has been introduced for nearly 30 years， and with extensive research on its pathogenesis， diagnostic criteria， and treatment strategies， related consensus statements and guidelines have been constantly updated in China and globally； however， there is still a lack of a unified definition of ACLF， and such differences in definition may inevitably hinder the application and implementation of various treatment methods， prognostic scoring systems， and clinical recommendations. In recent years， hepatology experts have continuously proposed methods to unify the definition of ACLF， seeking common ground while reserving differences and drawing on the strengths of various definitions， in order to achieve a more unified definition of ACLF.
Authors and Affiliations
Manman XU, Yu. CHEN
Keywords
Related Articles
- EP ID EP753517
- DOI 10.12449/JCH241108
- Views 8
- Downloads 1
Unified consensus and evolution of the definition of acute-on-chronic liver failure： Seeking common ground while reserving differences
The concept of acute-on-chronic liver failure （ACLF） has been introduced for nearly 30 years， and with extensive research on its pathogenesis， diagnostic criteria， and treatment strategies， related consensus statem...
Interpretation of guideline for diagnosis and treatment of liver failure （2024 version）
In 2024， Liver Failure and Artificial Liver Group， Chinese Society of Infectious Diseases， Chinese Medical Association and Chinese Society of Hepatology， Chinese Medical Association updated Guideline for diagnosis an...
Role of peripheral clock genes in the progression， prevention， and treatment of nonalcoholic steatohepatitis
As a severe clinical manifestation of nonalcoholic fatty liver disease， nonalcoholic steatohepatitis （NASH） is characterized by lipid deposition and inflammatory damage in the liver. At present， clinical medications...
Clinical features and prognosis of hepatocellular carcinoma： A single-center study of 850 cases
[Objective] To investigate the clinical features and prognosis of hepatocellular carcinoma （HCC）. [Methods] Medical records were collected from 850 HCC patients who were admitted to Hubei Provincial Hospital of Traditi...
Advances in the application of endoscopic ultrasonography in the diagnosis and treatment of cholangiocarcinoma
Endoscopic ultrasonography （EUS） can not only directly observe the morphology of the lumens of the digestive tract through the endoscope， but also perform real-time dynamic ultrasound scanning to obtain the layers of...